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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLVS2 All Species: 31.82
Human Site: T260 Identified Species: 70
UniProt: Q5SYC1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5SYC1 NP_001010852.2 327 38000 T260 L P P Y D M G T W A R T L L D
Chimpanzee Pan troglodytes XP_001158960 304 35294 N234 F L H G N N L N S L H Q L I H
Rhesus Macaque Macaca mulatta XP_001091304 354 40742 T282 L P P Y D M G T W A R T L L G
Dog Lupus familis XP_544098 354 40730 T282 L P P Y D M G T W A R T L L G
Cat Felis silvestris
Mouse Mus musculus Q8BG92 327 37936 T260 L P P Y D M G T W A R T L L D
Rat Rattus norvegicus A6JUQ6 327 37898 T260 L P P Y D M G T W A R T L L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513318 344 39097 D279 P R A L G R L D V P V P Q S G
Chicken Gallus gallus XP_419223 332 38227 T260 L P P Y D M G T W A R T L L G
Frog Xenopus laevis Q5M7E1 332 38511 T260 L P P Y D M G T W A R T L L G
Zebra Danio Brachydanio rerio Q5SPP0 329 38101 T260 L P P Y D M G T W A R T L L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SCU1 409 46492 T328 I E G G A T I T W D I V V G G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.6 74.8 74.8 N.A. 97.8 98.7 N.A. 53.4 79.8 78.6 88.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 84 83 83 N.A. 99.6 99.3 N.A. 63.9 88.2 87.9 95.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 93.3 93.3 N.A. 100 100 N.A. 0 93.3 93.3 100 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 93.3 93.3 N.A. 100 100 N.A. 0 93.3 93.3 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 22.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 0 0 0 0 73 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 73 0 0 10 0 10 0 0 0 0 37 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 19 10 0 73 0 0 0 0 0 0 10 55 % G
% His: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 10 % H
% Ile: 10 0 0 0 0 0 10 0 0 0 10 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 73 10 0 10 0 0 19 0 0 10 0 0 82 73 0 % L
% Met: 0 0 0 0 0 73 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 10 0 10 0 0 0 0 0 0 0 % N
% Pro: 10 73 73 0 0 0 0 0 0 10 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % Q
% Arg: 0 10 0 0 0 10 0 0 0 0 73 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % S
% Thr: 0 0 0 0 0 10 0 82 0 0 0 73 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 10 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 82 0 0 0 0 0 0 % W
% Tyr: 0 0 0 73 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _