KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NHSL1
All Species:
4.55
Human Site:
S544
Identified Species:
12.5
UniProt:
Q5SYE7
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SYE7
NP_065197.1
1610
170668
S544
V
D
G
K
S
E
S
S
Y
S
G
G
G
G
H
Chimpanzee
Pan troglodytes
XP_001171693
1611
170460
S539
S
T
P
T
S
N
M
S
S
C
S
L
D
Q
T
Rhesus Macaque
Macaca mulatta
XP_001095123
1561
165521
H525
R
A
S
P
L
K
P
H
V
A
T
P
G
Y
S
Dog
Lupus familis
XP_533424
1576
166550
P528
L
K
A
H
L
T
T
P
G
Y
S
T
P
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CAF4
1587
169401
S536
P
S
D
V
D
G
K
S
E
C
S
Y
S
G
D
Rat
Rattus norvegicus
XP_002725496
1593
169646
S540
V
D
G
K
S
E
C
S
S
S
G
D
R
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509254
1768
188530
E536
Q
D
S
D
G
R
S
E
S
S
G
S
G
D
R
Chicken
Gallus gallus
XP_419717
1652
178098
G549
R
S
E
S
S
Y
S
G
E
R
T
Q
G
V
V
Frog
Xenopus laevis
NP_001088582
1443
160071
S407
S
R
M
A
D
S
G
S
C
D
I
S
S
N
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.8
91.2
74.7
N.A.
75.9
75.8
N.A.
57.9
57.8
21.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.9
93.1
79.8
N.A.
82.5
81.9
N.A.
66.7
69.4
38
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
6.6
N.A.
13.3
66.6
N.A.
33.3
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
20
20
N.A.
13.3
66.6
N.A.
33.3
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
12
0
0
0
0
0
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
12
0
12
23
0
0
0
0
12
% C
% Asp:
0
34
12
12
23
0
0
0
0
12
0
12
12
12
12
% D
% Glu:
0
0
12
0
0
23
0
12
23
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
23
0
12
12
12
12
12
0
34
12
45
45
0
% G
% His:
0
0
0
12
0
0
0
12
0
0
0
0
0
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
0
12
0
23
0
12
12
0
0
0
0
0
0
0
0
% K
% Leu:
12
0
0
0
23
0
0
0
0
0
0
12
0
0
0
% L
% Met:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
0
0
0
0
0
0
12
0
% N
% Pro:
12
0
12
12
0
0
12
12
0
0
0
12
12
0
0
% P
% Gln:
12
0
0
0
0
0
0
0
0
0
0
12
0
12
0
% Q
% Arg:
23
12
0
0
0
12
0
0
0
12
0
0
12
0
12
% R
% Ser:
23
23
23
12
45
12
34
56
34
34
34
23
23
0
34
% S
% Thr:
0
12
0
12
0
12
12
0
0
0
23
12
0
0
12
% T
% Val:
23
0
0
12
0
0
0
0
12
0
0
0
0
12
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
0
12
12
0
12
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _