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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FREM2
All Species:
31.21
Human Site:
Y2433
Identified Species:
98.1
UniProt:
Q5SZK8
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5SZK8
NP_997244.3
3169
351157
Y2433
I
N
D
T
L
T
R
Y
R
W
L
I
S
A
P
Chimpanzee
Pan troglodytes
XP_522664
3169
351069
Y2433
I
N
D
T
L
T
R
Y
R
W
L
I
S
A
P
Rhesus Macaque
Macaca mulatta
XP_001086486
3170
351093
Y2434
I
N
D
T
L
T
R
Y
R
W
L
T
S
A
P
Dog
Lupus familis
XP_543127
3169
350410
Y2430
I
N
D
T
L
T
R
Y
R
W
L
I
S
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6NVD0
3160
350621
Y2422
I
N
D
T
L
T
R
Y
R
W
L
I
S
A
P
Rat
Rattus norvegicus
XP_227142
3158
350238
Y2420
I
N
D
T
L
T
R
Y
R
W
L
T
S
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417087
3168
351300
Y2429
I
N
N
T
L
T
Q
Y
R
W
L
V
S
A
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001131133
3116
347686
Y2380
I
N
N
T
L
T
R
Y
R
W
L
V
S
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.5
89.5
N.A.
88.1
88.3
N.A.
N.A.
76.8
N.A.
68
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.8
94.7
N.A.
93.7
93.5
N.A.
N.A.
86.8
N.A.
82.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
100
93.3
N.A.
N.A.
80
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
100
93.3
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
75
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
100
0
0
0
0
0
0
0
0
0
0
50
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
100
0
0
0
0
0
100
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
100
25
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% P
% Gln:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
88
0
100
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% S
% Thr:
0
0
0
100
0
100
0
0
0
0
0
25
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _