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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC18
All Species:
16.67
Human Site:
S133
Identified Species:
45.83
UniProt:
Q5T0N1
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T0N1
NP_660153.3
1121
125689
S133
P
L
H
P
V
Q
G
S
P
L
E
T
P
R
S
Chimpanzee
Pan troglodytes
XP_508172
1122
125861
S133
P
L
H
P
V
Q
G
S
P
L
E
T
P
R
S
Rhesus Macaque
Macaca mulatta
XP_001103065
1122
125916
S133
P
L
H
P
V
Q
G
S
P
L
E
T
P
R
S
Dog
Lupus familis
XP_536387
1135
127604
S221
P
L
H
P
V
P
G
S
P
L
E
P
L
R
S
Cat
Felis silvestris
Mouse
Mus musculus
NP_083974
1141
128258
S133
P
L
H
P
V
P
G
S
P
L
E
T
P
L
P
Rat
Rattus norvegicus
NP_001101840
320
35069
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505579
816
92460
Chicken
Gallus gallus
XP_001232754
1260
139523
T305
A
P
L
Y
A
A
S
T
S
P
S
E
S
L
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692963
1050
117735
D137
A
V
T
G
S
P
A
D
V
A
L
R
E
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.1
81.3
N.A.
79.9
23.7
N.A.
47.3
50
N.A.
46.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
99.1
86.1
N.A.
87.5
25.8
N.A.
58.5
65
N.A.
63.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
80
0
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
80
0
N.A.
0
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
0
0
12
12
12
0
0
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
56
12
12
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
56
0
0
0
0
0
0
0
12
% G
% His:
0
0
56
0
0
0
0
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
56
12
0
0
0
0
0
0
56
12
0
12
23
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
56
12
0
56
0
34
0
0
56
12
0
12
45
0
12
% P
% Gln:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
12
0
45
0
% R
% Ser:
0
0
0
0
12
0
12
56
12
0
12
0
12
0
45
% S
% Thr:
0
0
12
0
0
0
0
12
0
0
0
45
0
0
0
% T
% Val:
0
12
0
0
56
0
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _