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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARCH8
All Species:
12.12
Human Site:
S253
Identified Species:
29.63
UniProt:
Q5T0T0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T0T0
NP_001002265.1
291
32965
S253
K
K
N
I
F
E
K
S
P
L
T
E
P
N
F
Chimpanzee
Pan troglodytes
XP_001159315
291
32875
S253
K
K
N
I
F
E
K
S
P
L
T
E
P
T
F
Rhesus Macaque
Macaca mulatta
XP_001102718
291
32877
S253
K
K
N
I
F
E
K
S
P
L
A
E
P
N
F
Dog
Lupus familis
XP_848387
289
32745
A252
K
S
I
F
E
N
S
A
L
T
E
P
N
F
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBD2
286
32225
S249
K
K
N
I
F
E
K
S
A
L
T
E
P
T
L
Rat
Rattus norvegicus
Q5I0I2
246
27151
K209
Q
L
Y
S
E
W
R
K
T
N
Q
K
V
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507971
285
31749
F248
A
K
K
L
E
K
N
F
S
C
N
M
T
V
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5XH39
264
30118
V227
K
K
I
F
E
K
S
V
I
I
E
P
N
L
E
Zebra Danio
Brachydanio rerio
Q1LVZ2
249
27919
R212
Q
L
Y
S
E
W
R
R
T
N
Q
K
V
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784298
330
36529
G273
V
V
A
V
G
F
T
G
G
L
V
F
M
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
97.9
89.6
N.A.
91
23.3
N.A.
68
N.A.
78
26.4
N.A.
N.A.
N.A.
N.A.
48.7
Protein Similarity:
100
98.9
98.6
93.4
N.A.
94.1
41.2
N.A.
78
N.A.
80.7
45.3
N.A.
N.A.
N.A.
N.A.
65.1
P-Site Identity:
100
93.3
93.3
6.6
N.A.
80
0
N.A.
6.6
N.A.
13.3
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
13.3
N.A.
80
20
N.A.
20
N.A.
26.6
20
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
10
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
50
40
0
0
0
0
20
40
0
0
20
% E
% Phe:
0
0
0
20
40
10
0
10
0
0
0
10
0
10
30
% F
% Gly:
0
0
0
0
10
0
0
10
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
20
40
0
0
0
0
10
10
0
0
0
0
0
% I
% Lys:
60
60
10
0
0
20
40
10
0
0
0
20
0
0
0
% K
% Leu:
0
20
0
10
0
0
0
0
10
50
0
0
0
10
30
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% M
% Asn:
0
0
40
0
0
10
10
0
0
20
10
0
20
20
0
% N
% Pro:
0
0
0
0
0
0
0
0
30
0
0
20
40
0
0
% P
% Gln:
20
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
20
10
0
0
0
0
0
20
0
% R
% Ser:
0
10
0
20
0
0
20
40
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
20
10
30
0
10
20
0
% T
% Val:
10
10
0
10
0
0
0
10
0
0
10
0
20
10
10
% V
% Trp:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
20
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _