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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MARCH8 All Species: 12.12
Human Site: S59 Identified Species: 29.63
UniProt: Q5T0T0 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T0T0 NP_001002265.1 291 32965 S59 A G S P P S A S A P A P V S S
Chimpanzee Pan troglodytes XP_001159315 291 32875 S59 A G S P P S A S T P A P V S S
Rhesus Macaque Macaca mulatta XP_001102718 291 32877 S59 A G S P P S A S A P A P V S S
Dog Lupus familis XP_848387 289 32745 A58 K A G G S S L A S A P A S A F
Cat Felis silvestris
Mouse Mus musculus Q9DBD2 286 32225 S55 K A G S S P P S T T A P V S A
Rat Rattus norvegicus Q5I0I2 246 27151 D15 H L P G S L C D C S S S P A F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507971 285 31749 P54 N I S K A S S P T T G T A P R
Chicken Gallus gallus
Frog Xenopus laevis Q5XH39 264 30118 S33 S K A G S P T S V S A P S R F
Zebra Danio Brachydanio rerio Q1LVZ2 249 27919 G18 G S L C D C T G N A A L S K T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784298 330 36529 L79 V C Q S S S Y L P G S V T Q S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 97.9 89.6 N.A. 91 23.3 N.A. 68 N.A. 78 26.4 N.A. N.A. N.A. N.A. 48.7
Protein Similarity: 100 98.9 98.6 93.4 N.A. 94.1 41.2 N.A. 78 N.A. 80.7 45.3 N.A. N.A. N.A. N.A. 65.1
P-Site Identity: 100 93.3 100 6.6 N.A. 33.3 0 N.A. 13.3 N.A. 20 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 93.3 100 26.6 N.A. 40 13.3 N.A. 20 N.A. 33.3 13.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 30 20 10 0 10 0 30 10 20 20 60 10 10 20 10 % A
% Cys: 0 10 0 10 0 10 10 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30 % F
% Gly: 10 30 20 30 0 0 0 10 0 10 10 0 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 20 10 0 10 0 0 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 10 10 0 0 10 10 10 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % N
% Pro: 0 0 10 30 30 20 10 10 10 30 10 50 10 10 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % R
% Ser: 10 10 40 20 50 60 10 50 10 20 20 10 30 40 40 % S
% Thr: 0 0 0 0 0 0 20 0 30 20 0 10 10 0 10 % T
% Val: 10 0 0 0 0 0 0 0 10 0 0 10 40 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _