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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MARCH8 All Species: 15.76
Human Site: S75 Identified Species: 38.52
UniProt: Q5T0T0 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T0T0 NP_001002265.1 291 32965 S75 S R T S I T P S S Q D I C R I
Chimpanzee Pan troglodytes XP_001159315 291 32875 S75 S R T S I T P S S Q D I C R I
Rhesus Macaque Macaca mulatta XP_001102718 291 32877 S75 S R T S I T P S S Q D I C R I
Dog Lupus familis XP_848387 289 32745 N74 R A S V T P S N Q D I C R I C
Cat Felis silvestris
Mouse Mus musculus Q9DBD2 286 32225 S71 S R T S V T P S N Q D I C R I
Rat Rattus norvegicus Q5I0I2 246 27151 L31 K V V E A T G L G P P Q Y V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507971 285 31749 P70 Q S R L S V C P S T Q D I C R
Chicken Gallus gallus
Frog Xenopus laevis Q5XH39 264 30118 S49 R T S V T P S S Q D I C R I C
Zebra Danio Brachydanio rerio Q1LVZ2 249 27919 A34 E E A D N R R A Q Y V T Q V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784298 330 36529 S95 S R P S T A S S I S R G S K A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 97.9 89.6 N.A. 91 23.3 N.A. 68 N.A. 78 26.4 N.A. N.A. N.A. N.A. 48.7
Protein Similarity: 100 98.9 98.6 93.4 N.A. 94.1 41.2 N.A. 78 N.A. 80.7 45.3 N.A. N.A. N.A. N.A. 65.1
P-Site Identity: 100 100 100 0 N.A. 86.6 6.6 N.A. 6.6 N.A. 6.6 0 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 100 13.3 N.A. 100 6.6 N.A. 6.6 N.A. 13.3 6.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 10 10 0 10 0 0 0 0 0 0 20 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 20 40 10 20 % C
% Asp: 0 0 0 10 0 0 0 0 0 20 40 10 0 0 0 % D
% Glu: 10 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 10 0 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 30 0 0 0 10 0 20 40 10 20 40 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 10 10 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 20 40 10 0 10 10 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 30 40 10 10 10 0 0 % Q
% Arg: 20 50 10 0 0 10 10 0 0 0 10 0 20 40 10 % R
% Ser: 50 10 20 50 10 0 30 60 40 10 0 0 10 0 0 % S
% Thr: 0 10 40 0 30 50 0 0 0 10 0 10 0 0 10 % T
% Val: 0 10 10 20 10 10 0 0 0 0 10 0 0 20 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _