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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MARCH8 All Species: 7.88
Human Site: T256 Identified Species: 19.26
UniProt: Q5T0T0 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T0T0 NP_001002265.1 291 32965 T256 I F E K S P L T E P N F E N K
Chimpanzee Pan troglodytes XP_001159315 291 32875 T256 I F E K S P L T E P T F E N K
Rhesus Macaque Macaca mulatta XP_001102718 291 32877 A256 I F E K S P L A E P N F E N K
Dog Lupus familis XP_848387 289 32745 E255 F E N S A L T E P N F E N K D
Cat Felis silvestris
Mouse Mus musculus Q9DBD2 286 32225 T252 I F E K S A L T E P T L E N K
Rat Rattus norvegicus Q5I0I2 246 27151 Q212 S E W R K T N Q K V R L K I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507971 285 31749 N251 L E K N F S C N M T V D T K D
Chicken Gallus gallus
Frog Xenopus laevis Q5XH39 264 30118 E230 F E K S V I I E P N L E S K E
Zebra Danio Brachydanio rerio Q1LVZ2 249 27919 Q215 S E W R R T N Q K V R L L I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784298 330 36529 V276 V G F T G G L V F M Y V Q C K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 97.9 89.6 N.A. 91 23.3 N.A. 68 N.A. 78 26.4 N.A. N.A. N.A. N.A. 48.7
Protein Similarity: 100 98.9 98.6 93.4 N.A. 94.1 41.2 N.A. 78 N.A. 80.7 45.3 N.A. N.A. N.A. N.A. 65.1
P-Site Identity: 100 93.3 93.3 0 N.A. 80 0 N.A. 0 N.A. 0 0 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 93.3 93.3 6.6 N.A. 80 26.6 N.A. 13.3 N.A. 20 13.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 10 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 20 % D
% Glu: 0 50 40 0 0 0 0 20 40 0 0 20 40 0 10 % E
% Phe: 20 40 10 0 10 0 0 0 10 0 10 30 0 0 0 % F
% Gly: 0 10 0 0 10 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 40 0 0 0 0 10 10 0 0 0 0 0 0 20 0 % I
% Lys: 0 0 20 40 10 0 0 0 20 0 0 0 10 30 50 % K
% Leu: 10 0 0 0 0 10 50 0 0 0 10 30 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % M
% Asn: 0 0 10 10 0 0 20 10 0 20 20 0 10 40 0 % N
% Pro: 0 0 0 0 0 30 0 0 20 40 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 20 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 20 10 0 0 0 0 0 20 0 0 0 10 % R
% Ser: 20 0 0 20 40 10 0 0 0 0 0 0 10 0 0 % S
% Thr: 0 0 0 10 0 20 10 30 0 10 20 0 10 0 0 % T
% Val: 10 0 0 0 10 0 0 10 0 20 10 10 0 0 0 % V
% Trp: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _