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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARCH8
All Species:
9.7
Human Site:
T279
Identified Species:
23.7
UniProt:
Q5T0T0
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T0T0
NP_001002265.1
291
32965
T279
D
T
N
S
S
C
C
T
E
P
E
D
T
G
A
Chimpanzee
Pan troglodytes
XP_001159315
291
32875
T279
D
T
N
S
S
C
C
T
E
P
E
D
T
G
A
Rhesus Macaque
Macaca mulatta
XP_001102718
291
32877
T279
D
T
N
S
S
C
C
T
E
P
E
D
T
G
A
Dog
Lupus familis
XP_848387
289
32745
E278
T
N
S
S
C
W
T
E
P
E
D
T
G
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBD2
286
32225
E275
T
T
N
S
S
C
T
E
P
E
D
T
G
A
E
Rat
Rattus norvegicus
Q5I0I2
246
27151
G235
H
H
S
L
L
A
T
G
L
L
K
K
V
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507971
285
31749
S274
T
G
T
G
S
P
P
S
L
E
A
G
A
P
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5XH39
264
30118
E253
T
N
S
S
Y
Y
T
E
P
E
D
C
G
A
A
Zebra Danio
Brachydanio rerio
Q1LVZ2
249
27919
K238
Q
H
S
L
L
S
T
K
L
L
K
K
T
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784298
330
36529
I299
L
K
A
Y
N
R
V
I
Y
V
Q
N
C
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
97.9
89.6
N.A.
91
23.3
N.A.
68
N.A.
78
26.4
N.A.
N.A.
N.A.
N.A.
48.7
Protein Similarity:
100
98.9
98.6
93.4
N.A.
94.1
41.2
N.A.
78
N.A.
80.7
45.3
N.A.
N.A.
N.A.
N.A.
65.1
P-Site Identity:
100
100
100
6.6
N.A.
33.3
0
N.A.
6.6
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
40
13.3
N.A.
13.3
N.A.
26.6
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
0
0
0
0
10
0
10
40
40
% A
% Cys:
0
0
0
0
10
40
30
0
0
0
0
10
10
0
0
% C
% Asp:
30
0
0
0
0
0
0
0
0
0
30
30
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
30
30
40
30
0
0
0
40
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
10
0
0
0
10
0
0
0
10
30
30
0
% G
% His:
10
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
10
0
0
20
20
0
0
0
% K
% Leu:
10
0
0
20
20
0
0
0
30
20
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
40
0
10
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
10
10
0
30
30
0
0
0
20
10
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
40
60
50
10
0
10
0
0
0
0
0
0
0
% S
% Thr:
40
40
10
0
0
0
50
30
0
0
0
20
40
10
0
% T
% Val:
0
0
0
0
0
0
10
0
0
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
10
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _