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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARCH8
All Species:
9.7
Human Site:
Y22
Identified Species:
23.7
UniProt:
Q5T0T0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T0T0
NP_001002265.1
291
32965
Y22
D
A
I
S
A
R
V
Y
R
S
K
T
K
E
K
Chimpanzee
Pan troglodytes
XP_001159315
291
32875
Y22
D
A
I
S
A
R
V
Y
R
S
K
T
K
E
K
Rhesus Macaque
Macaca mulatta
XP_001102718
291
32877
Y22
D
A
T
S
A
R
V
Y
R
S
K
T
K
E
K
Dog
Lupus familis
XP_848387
289
32745
I21
Q
D
A
T
S
A
R
I
Y
R
S
K
T
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBD2
286
32225
S18
I
P
S
Q
D
A
I
S
A
R
V
Y
R
S
K
Rat
Rattus norvegicus
Q5I0I2
246
27151
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507971
285
31749
N17
P
A
R
E
T
A
S
N
G
R
S
S
L
G
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5XH39
264
30118
Zebra Danio
Brachydanio rerio
Q1LVZ2
249
27919
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784298
330
36529
R42
K
G
P
S
A
K
C
R
S
Q
S
E
R
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
97.9
89.6
N.A.
91
23.3
N.A.
68
N.A.
78
26.4
N.A.
N.A.
N.A.
N.A.
48.7
Protein Similarity:
100
98.9
98.6
93.4
N.A.
94.1
41.2
N.A.
78
N.A.
80.7
45.3
N.A.
N.A.
N.A.
N.A.
65.1
P-Site Identity:
100
100
93.3
0
N.A.
6.6
0
N.A.
6.6
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
26.6
N.A.
20
0
N.A.
20
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
40
10
0
40
30
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
30
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
10
0
30
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
10
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
20
0
0
0
10
10
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
10
0
0
0
0
30
10
30
10
40
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
10
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
30
10
10
30
30
0
0
20
10
20
% R
% Ser:
0
0
10
40
10
0
10
10
10
30
30
10
0
10
0
% S
% Thr:
0
0
10
10
10
0
0
0
0
0
0
30
10
0
0
% T
% Val:
0
0
0
0
0
0
30
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
30
10
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _