KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THEM4
All Species:
10
Human Site:
S47
Identified Species:
24.44
UniProt:
Q5T1C6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1C6
NP_444283.2
240
27130
S47
E
V
I
L
K
D
C
S
V
P
N
P
S
W
N
Chimpanzee
Pan troglodytes
XP_513806
240
27259
S47
E
V
I
L
K
D
C
S
V
P
N
P
S
W
N
Rhesus Macaque
Macaca mulatta
XP_001108917
116
12553
Dog
Lupus familis
XP_851465
331
35313
S140
E
V
L
H
V
D
H
S
L
P
N
P
S
W
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3UUI3
230
26013
W44
Y
A
L
P
N
P
S
W
T
K
D
L
R
L
L
Rat
Rattus norvegicus
Q566R0
230
26071
W44
Y
A
L
P
N
P
S
W
T
K
D
L
R
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512354
152
16267
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GLK2
222
24962
S36
Y
T
A
P
K
F
Y
S
Q
E
A
P
R
D
Y
Zebra Danio
Brachydanio rerio
NP_001074103
222
24562
E36
P
N
P
S
W
S
P
E
M
R
K
F
Y
D
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188893
199
21898
T13
Q
A
I
N
P
K
S
T
S
E
R
D
L
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
45.4
49.8
N.A.
68.3
69.1
N.A.
36.6
N.A.
47.9
38.7
N.A.
N.A.
N.A.
N.A.
30.8
Protein Similarity:
100
97.9
48.3
58.6
N.A.
81.6
82
N.A.
50
N.A.
65.8
54.5
N.A.
N.A.
N.A.
N.A.
50.4
P-Site Identity:
100
100
0
66.6
N.A.
0
0
N.A.
0
N.A.
20
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
0
80
N.A.
13.3
13.3
N.A.
0
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
10
0
0
0
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
30
0
0
0
0
20
10
0
20
0
% D
% Glu:
30
0
0
0
0
0
0
10
0
20
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
30
10
0
0
0
20
10
0
0
0
0
% K
% Leu:
0
0
30
20
0
0
0
0
10
0
0
20
10
20
20
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
20
0
0
0
0
0
30
0
0
0
30
% N
% Pro:
10
0
10
30
10
20
10
0
0
30
0
40
0
10
0
% P
% Gln:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
10
0
30
0
0
% R
% Ser:
0
0
0
10
0
10
30
40
10
0
0
0
30
0
0
% S
% Thr:
0
10
0
0
0
0
0
10
20
0
0
0
0
0
0
% T
% Val:
0
30
0
0
10
0
0
0
20
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
20
0
0
0
0
0
30
0
% W
% Tyr:
30
0
0
0
0
0
10
0
0
0
0
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _