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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBP15
All Species:
12.12
Human Site:
S1140
Identified Species:
29.63
UniProt:
Q5T1M5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1M5
NP_056073.1
1219
133630
S1140
G
P
H
K
E
L
S
S
T
E
A
G
S
T
V
Chimpanzee
Pan troglodytes
XP_520196
1314
142629
S1235
G
P
H
K
E
L
S
S
T
E
A
G
S
T
V
Rhesus Macaque
Macaca mulatta
XP_001098655
1299
142252
S1220
G
P
H
E
E
L
L
S
T
E
A
G
S
T
V
Dog
Lupus familis
XP_538799
1347
147406
S1280
S
P
T
V
G
T
A
S
G
P
N
Q
Y
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6P9Q6
1216
132942
D1135
G
P
R
E
T
L
L
D
T
E
L
A
S
A
A
Rat
Rattus norvegicus
XP_342847
1215
133044
T1137
G
P
C
E
V
M
D
T
E
R
A
A
A
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506981
1181
129059
P1102
K
P
E
L
D
A
S
P
S
A
V
E
L
P
V
Chicken
Gallus gallus
XP_415541
1169
127681
E1101
L
A
D
K
P
V
A
E
Q
E
A
E
E
P
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001340227
782
87845
L716
Q
Q
E
V
L
Q
L
L
M
Q
L
R
K
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789663
743
84695
Q677
T
R
I
K
E
L
I
Q
E
K
A
A
A
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
90.9
75.8
N.A.
79.9
79.2
N.A.
66
56.5
N.A.
29.7
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
100
86.9
92.2
81.3
N.A.
86.9
86.5
N.A.
75.5
69.9
N.A.
42.9
N.A.
N.A.
N.A.
N.A.
37.4
P-Site Identity:
100
100
86.6
13.3
N.A.
40
20
N.A.
20
26.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
93.3
26.6
N.A.
46.6
46.6
N.A.
33.3
40
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
20
0
0
10
60
30
20
30
20
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
10
10
0
0
0
0
0
10
0
% D
% Glu:
0
0
20
30
40
0
0
10
20
50
0
20
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
0
0
10
0
0
0
10
0
0
30
0
0
0
% G
% His:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
40
0
0
0
0
0
10
0
0
10
0
0
% K
% Leu:
10
0
0
10
10
50
30
10
0
0
20
0
10
0
0
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
70
0
0
10
0
0
10
0
10
0
0
0
20
0
% P
% Gln:
10
10
0
0
0
10
0
10
10
10
0
10
0
0
10
% Q
% Arg:
0
10
10
0
0
0
0
0
0
10
0
10
0
0
10
% R
% Ser:
10
0
0
0
0
0
30
40
10
0
0
0
40
10
0
% S
% Thr:
10
0
10
0
10
10
0
10
40
0
0
0
0
30
10
% T
% Val:
0
0
0
20
10
10
0
0
0
0
10
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _