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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX59
All Species:
23.03
Human Site:
S474
Identified Species:
33.78
UniProt:
Q5T1V6
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1V6
NP_001026895.2
619
68810
S474
I
T
G
L
K
S
I
S
I
H
S
E
K
S
Q
Chimpanzee
Pan troglodytes
XP_001143546
619
68778
S474
I
T
G
L
K
S
I
S
I
H
S
E
K
S
Q
Rhesus Macaque
Macaca mulatta
XP_001109688
319
35696
I175
T
G
L
K
S
I
S
I
H
S
E
K
S
Q
I
Dog
Lupus familis
XP_537128
620
68704
S475
I
T
G
L
K
S
V
S
I
H
S
E
K
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBN9
619
68216
S474
I
T
G
L
N
S
T
S
I
H
S
E
K
S
Q
Rat
Rattus norvegicus
Q66HG7
589
65047
S444
I
T
G
L
S
S
T
S
I
H
S
E
K
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520980
538
59378
E395
A
T
I
P
V
G
I
E
Q
L
A
N
Q
L
L
Chicken
Gallus gallus
XP_422189
625
69278
S480
I
T
G
L
Q
C
T
S
M
H
S
E
K
S
Q
Frog
Xenopus laevis
NP_001106297
254
27959
P111
L
V
G
G
M
P
L
P
P
Q
I
H
R
L
K
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
G582
L
K
L
L
E
I
L
G
H
Y
Q
E
K
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
S486
S
K
L
I
E
I
L
S
E
Q
A
D
G
T
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198909
620
68882
A472
P
K
H
F
R
P
P
A
I
V
F
V
D
S
K
Poplar Tree
Populus trichocarpa
XP_002320399
524
57616
I381
I
V
Y
V
G
S
R
I
G
A
D
L
L
S
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3EBD3
505
55199
V362
H
F
K
P
P
A
V
V
Y
V
S
S
R
V
G
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
A440
M
Q
N
F
K
A
T
A
I
H
G
D
R
T
Q
Red Bread Mold
Neurospora crassa
Q7SEL0
728
82594
L560
K
K
R
L
Q
E
I
L
N
S
G
Q
F
K
P
Conservation
Percent
Protein Identity:
100
99
51
89.8
N.A.
83.6
79.8
N.A.
61.8
72.3
30.2
22.3
N.A.
27.6
N.A.
N.A.
32.1
Protein Similarity:
100
99.8
51.3
93.3
N.A.
89.6
86.7
N.A.
71.5
84.3
35.3
37.3
N.A.
45.8
N.A.
N.A.
52.4
P-Site Identity:
100
100
0
93.3
N.A.
86.6
86.6
N.A.
13.3
73.3
6.6
20
N.A.
6.6
N.A.
N.A.
13.3
P-Site Similarity:
100
100
6.6
100
N.A.
86.6
86.6
N.A.
26.6
86.6
33.3
46.6
N.A.
46.6
N.A.
N.A.
33.3
Percent
Protein Identity:
40.7
N.A.
N.A.
38.1
26.3
26.9
Protein Similarity:
58
N.A.
N.A.
56.2
46.3
46.4
P-Site Identity:
20
N.A.
N.A.
6.6
26.6
13.3
P-Site Similarity:
26.6
N.A.
N.A.
26.6
66.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
13
0
13
0
7
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
7
13
7
0
0
% D
% Glu:
0
0
0
0
13
7
0
7
7
0
7
44
0
0
0
% E
% Phe:
0
7
0
13
0
0
0
0
0
0
7
0
7
0
0
% F
% Gly:
0
7
44
7
7
7
0
7
7
0
13
0
7
7
7
% G
% His:
7
0
7
0
0
0
0
0
13
44
0
7
0
0
0
% H
% Ile:
44
0
7
7
0
19
25
13
44
0
7
0
0
0
13
% I
% Lys:
7
25
7
7
25
0
0
0
0
0
0
7
44
7
13
% K
% Leu:
13
0
19
50
0
0
19
7
0
7
0
7
7
13
7
% L
% Met:
7
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
7
0
0
0
7
0
0
7
0
0
7
% N
% Pro:
7
0
0
13
7
13
7
7
7
0
0
0
0
0
7
% P
% Gln:
0
7
0
0
13
0
0
0
7
13
7
7
7
7
44
% Q
% Arg:
0
0
7
0
7
0
7
0
0
0
0
0
19
0
0
% R
% Ser:
7
0
0
0
13
38
7
44
0
13
44
7
7
50
7
% S
% Thr:
7
44
0
0
0
0
25
0
0
0
0
0
0
13
0
% T
% Val:
0
13
0
7
7
0
13
7
0
13
0
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
7
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _