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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX59
All Species:
31.52
Human Site:
Y223
Identified Species:
46.22
UniProt:
Q5T1V6
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1V6
NP_001026895.2
619
68810
Y223
H
N
L
K
K
S
G
Y
E
V
P
T
P
I
Q
Chimpanzee
Pan troglodytes
XP_001143546
619
68778
Y223
H
N
L
K
K
S
G
Y
E
V
P
T
P
I
Q
Rhesus Macaque
Macaca mulatta
XP_001109688
319
35696
Dog
Lupus familis
XP_537128
620
68704
Y224
H
N
L
K
T
S
G
Y
E
V
P
T
P
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBN9
619
68216
Y223
Q
N
L
K
K
S
G
Y
E
V
P
T
P
I
Q
Rat
Rattus norvegicus
Q66HG7
589
65047
Y223
Q
N
L
K
K
S
G
Y
E
V
P
T
P
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520980
538
59378
Q197
L
Q
L
G
I
S
V
Q
G
Q
G
V
S
R
P
Chicken
Gallus gallus
XP_422189
625
69278
Y229
S
N
L
K
N
S
G
Y
E
V
P
T
P
I
Q
Frog
Xenopus laevis
NP_001106297
254
27959
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
Y360
N
A
L
K
K
H
N
Y
E
K
P
T
P
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
Y265
D
N
V
N
K
S
G
Y
K
I
P
T
P
I
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198909
620
68882
Q79
N
L
V
R
R
G
I
Q
T
T
A
P
K
T
K
Poplar Tree
Populus trichocarpa
XP_002320399
524
57616
V183
A
S
F
L
V
P
V
V
S
R
C
A
T
F
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3EBD3
505
55199
F164
G
S
G
K
T
A
S
F
L
V
P
I
I
S
R
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
F208
G
S
G
K
T
G
G
F
L
F
P
L
F
T
E
Red Bread Mold
Neurospora crassa
Q7SEL0
728
82594
Y313
D
I
V
K
N
V
G
Y
D
E
P
T
P
I
Q
Conservation
Percent
Protein Identity:
100
99
51
89.8
N.A.
83.6
79.8
N.A.
61.8
72.3
30.2
22.3
N.A.
27.6
N.A.
N.A.
32.1
Protein Similarity:
100
99.8
51.3
93.3
N.A.
89.6
86.7
N.A.
71.5
84.3
35.3
37.3
N.A.
45.8
N.A.
N.A.
52.4
P-Site Identity:
100
100
0
93.3
N.A.
93.3
93.3
N.A.
13.3
86.6
0
66.6
N.A.
66.6
N.A.
N.A.
0
P-Site Similarity:
100
100
0
93.3
N.A.
93.3
93.3
N.A.
13.3
86.6
0
73.3
N.A.
86.6
N.A.
N.A.
33.3
Percent
Protein Identity:
40.7
N.A.
N.A.
38.1
26.3
26.9
Protein Similarity:
58
N.A.
N.A.
56.2
46.3
46.4
P-Site Identity:
0
N.A.
N.A.
20
20
53.3
P-Site Similarity:
13.3
N.A.
N.A.
46.6
40
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
7
0
0
0
0
7
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
13
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
44
7
0
0
0
0
7
% E
% Phe:
0
0
7
0
0
0
0
13
0
7
0
0
7
7
0
% F
% Gly:
13
0
13
7
0
13
57
0
7
0
7
0
0
0
0
% G
% His:
19
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
0
7
0
0
7
0
7
7
57
0
% I
% Lys:
0
0
0
63
38
0
0
0
7
7
0
0
7
0
7
% K
% Leu:
7
7
50
7
0
0
0
0
13
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
44
0
7
13
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
69
7
57
0
7
% P
% Gln:
13
7
0
0
0
0
0
13
0
7
0
0
0
0
57
% Q
% Arg:
0
0
0
7
7
0
0
0
0
7
0
0
0
7
13
% R
% Ser:
7
19
0
0
0
50
7
0
7
0
0
0
7
7
0
% S
% Thr:
0
0
0
0
19
0
0
0
7
7
0
57
7
13
0
% T
% Val:
0
0
19
0
7
7
13
7
0
44
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
57
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _