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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BET3L All Species: 38.79
Human Site: S124 Identified Species: 60.95
UniProt: Q5T215 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T215 NP_001132916.1 181 20566 S124 E E L P A G R S S L C Y C N L
Chimpanzee Pan troglodytes XP_001161965 181 20646 S124 E E L P A G R S S L C Y C N L
Rhesus Macaque Macaca mulatta XP_001111406 181 20648 S124 E E L P A G R S S L C Y C N L
Dog Lupus familis XP_855356 284 31701 S227 E E L P A G R S S L C Y C N L
Cat Felis silvestris
Mouse Mus musculus Q4KL14 181 20745 S124 E E L P A G R S A L C Y C N L
Rat Rattus norvegicus XP_002725920 181 20721 S124 E E L P A G R S A L C Y C N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510481 182 20310 S125 V E L P D N H S T L I Y S N L
Chicken Gallus gallus Q5ZI57 180 20258 S123 V E L P D N H S S L I Y S N L
Frog Xenopus laevis NP_001080521 180 20336 S123 V E L P D N H S T L V Y S N L
Zebra Danio Brachydanio rerio NP_001003601 180 20361 S123 V E L P D N H S N L V Y S N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648312 178 20454 T121 V E L P P D L T N L R Y S A I
Honey Bee Apis mellifera XP_396163 178 20249 L121 V E L P D H C L N L K Y C N V
Nematode Worm Caenorhab. elegans P34605 181 19681 A122 T E L V Q V P A H L V S A G L
Sea Urchin Strong. purpuratus XP_795503 180 20140 S123 V E L P E D H S N L N Y S N V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36149 193 22111 K136 E L P M D A M K S L W Y S N I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.7 58.7 N.A. 92.8 91.7 N.A. 60.9 64 61.8 62.4 N.A. 46.4 49.7 38.6 54.7
Protein Similarity: 100 99.4 98.9 60.2 N.A. 96.6 96.1 N.A. 75.2 77.3 77.9 77.3 N.A. 66.3 70.1 55.7 74.5
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 53.3 60 53.3 53.3 N.A. 33.3 46.6 26.6 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 60 60 60 60 N.A. 53.3 60 33.3 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 44.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 65.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 40 7 0 7 14 0 0 0 7 7 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 40 0 47 0 0 % C
% Asp: 0 0 0 0 40 14 0 0 0 0 0 0 0 0 0 % D
% Glu: 47 94 0 0 7 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 40 0 0 0 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 7 34 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 14 0 0 0 14 % I
% Lys: 0 0 0 0 0 0 0 7 0 0 7 0 0 0 0 % K
% Leu: 0 7 94 0 0 0 7 7 0 100 0 0 0 0 74 % L
% Met: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 27 0 0 27 0 7 0 0 87 0 % N
% Pro: 0 0 7 87 7 0 7 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 40 0 0 0 7 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 74 40 0 0 7 47 0 0 % S
% Thr: 7 0 0 0 0 0 0 7 14 0 0 0 0 0 0 % T
% Val: 47 0 0 7 0 7 0 0 0 0 20 0 0 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 94 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _