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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BET3L All Species: 41.82
Human Site: T94 Identified Species: 65.71
UniProt: Q5T215 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T215 NP_001132916.1 181 20566 T94 L G I T P S V T C N N S S K N
Chimpanzee Pan troglodytes XP_001161965 181 20646 T94 L G I T P S V T C N N S S K N
Rhesus Macaque Macaca mulatta XP_001111406 181 20648 T94 L G I T P S V T C N N S S R N
Dog Lupus familis XP_855356 284 31701 T197 L G I T P S V T C N N S S R T
Cat Felis silvestris
Mouse Mus musculus Q4KL14 181 20745 T94 L G I T P S V T C H N S S R N
Rat Rattus norvegicus XP_002725920 181 20721 T94 L G T T P S V T C H N S S R N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510481 182 20310 T96 L G I T P S I T N W S P A G D
Chicken Gallus gallus Q5ZI57 180 20258 T94 L G I T P S I T N W S P G G D
Frog Xenopus laevis NP_001080521 180 20336 T94 L G V T P T I T N W S P A G D
Zebra Danio Brachydanio rerio NP_001003601 180 20361 T94 L G I T P S V T N W S P A G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648312 178 20454 W94 I Q P T I S N W S P A S D E F
Honey Bee Apis mellifera XP_396163 178 20249 A96 P T I T N W S A A G D E F S L
Nematode Worm Caenorhab. elegans P34605 181 19681 A95 Y L G I S A T A S S W T S G D
Sea Urchin Strong. purpuratus XP_795503 180 20140 S94 L G V T P S V S N W S P A G D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36149 193 22111 T106 L N I T P N I T N W S H N K D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.7 58.7 N.A. 92.8 91.7 N.A. 60.9 64 61.8 62.4 N.A. 46.4 49.7 38.6 54.7
Protein Similarity: 100 99.4 98.9 60.2 N.A. 96.6 96.1 N.A. 75.2 77.3 77.9 77.3 N.A. 66.3 70.1 55.7 74.5
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 80 N.A. 46.6 46.6 33.3 53.3 N.A. 20 13.3 6.6 40
P-Site Similarity: 100 100 100 93.3 N.A. 100 93.3 N.A. 73.3 66.6 73.3 73.3 N.A. 33.3 20 33.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 44.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 65.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 40 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 7 0 14 7 0 7 0 27 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 40 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 7 0 7 0 47 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 7 0 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % F
% Gly: 0 74 7 0 0 0 0 0 0 7 0 0 7 40 0 % G
% His: 0 0 0 0 0 0 0 0 0 14 0 7 0 0 0 % H
% Ile: 7 0 67 7 7 0 27 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % K
% Leu: 80 7 0 0 0 0 0 0 0 0 0 0 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 7 7 7 0 40 27 40 0 7 0 34 % N
% Pro: 7 0 7 0 80 0 0 0 0 7 0 34 0 0 0 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 27 0 % R
% Ser: 0 0 0 0 7 74 7 7 14 7 40 47 47 7 0 % S
% Thr: 0 7 7 94 0 7 7 74 0 0 0 7 0 0 7 % T
% Val: 0 0 14 0 0 0 54 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 7 0 7 0 40 7 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _