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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BET3L All Species: 19.7
Human Site: Y177 Identified Species: 30.95
UniProt: Q5T215 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T215 NP_001132916.1 181 20566 Y177 K K R D E K K Y R G K K _ _ _
Chimpanzee Pan troglodytes XP_001161965 181 20646 Y177 K K R D E K K Y R R K K _ _ _
Rhesus Macaque Macaca mulatta XP_001111406 181 20648 Y177 K K R D E K K Y R R K K _ _ _
Dog Lupus familis XP_855356 284 31701 Y280 K K L D E K K Y R R K K _ _ _
Cat Felis silvestris
Mouse Mus musculus Q4KL14 181 20745 Y177 K K L D E K K Y R R K K _ _ _
Rat Rattus norvegicus XP_002725920 181 20721 Y177 K K V D D K K Y R R K K _ _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510481 182 20310 P178 R R I E D N L P A G E E _ _ _
Chicken Gallus gallus Q5ZI57 180 20258 P176 R R I E D N L P A G E E _ _ _
Frog Xenopus laevis NP_001080521 180 20336 P176 K R I E D N L P A G E E _ _ _
Zebra Danio Brachydanio rerio NP_001003601 180 20361 P176 K R I E E N L P A G D E _ _ _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648312 178 20454 P174 R R L E E V I P A G E D _ _ _
Honey Bee Apis mellifera XP_396163 178 20249 P174 K R L E D A I P A G E D _ _ _
Nematode Worm Caenorhab. elegans P34605 181 19681 L171 R I R F D Q V L K D S L P A G
Sea Urchin Strong. purpuratus XP_795503 180 20140 P176 Q R L E D A L P A G E E _ _ _
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36149 193 22111 P189 R I L K D E I P I G E D _ _ _
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 97.7 58.7 N.A. 92.8 91.7 N.A. 60.9 64 61.8 62.4 N.A. 46.4 49.7 38.6 54.7
Protein Similarity: 100 99.4 98.9 60.2 N.A. 96.6 96.1 N.A. 75.2 77.3 77.9 77.3 N.A. 66.3 70.1 55.7 74.5
P-Site Identity: 100 91.6 91.6 83.3 N.A. 83.3 75 N.A. 8.3 8.3 16.6 25 N.A. 16.6 16.6 6.6 8.3
P-Site Similarity: 100 91.6 91.6 83.3 N.A. 83.3 83.3 N.A. 58.3 58.3 58.3 50 N.A. 50 50 40 58.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 44.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 65.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 8.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 41.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 14 0 0 47 0 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 40 54 0 0 0 0 7 7 20 0 0 0 % D
% Glu: 0 0 0 47 47 7 0 0 0 0 47 34 0 0 0 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 60 0 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 14 27 0 0 0 20 0 7 0 0 0 0 0 0 % I
% Lys: 60 40 0 7 0 40 40 0 7 0 40 40 0 0 0 % K
% Leu: 0 0 40 0 0 0 34 7 0 0 0 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 27 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 54 0 0 0 0 7 0 0 % P
% Gln: 7 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % Q
% Arg: 34 47 27 0 0 0 0 0 40 34 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 7 0 0 7 7 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 40 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 94 94 94 % _