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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C9orf114 All Species: 36.06
Human Site: S205 Identified Species: 52.89
UniProt: Q5T280 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T280 NP_057474.2 376 42009 S205 P T R P G H G S F V N C G M K
Chimpanzee Pan troglodytes XP_520300 437 48483 S266 P T R P G H G S F V N C G M K
Rhesus Macaque Macaca mulatta XP_001119071 143 15934
Dog Lupus familis XP_851147 396 44060 S205 P T R P G H G S F V N C G M K
Cat Felis silvestris
Mouse Mus musculus Q3UHX9 385 42939 S206 P T K A G H G S L V N C G M K
Rat Rattus norvegicus NP_001040575 242 26174 Q101 T V R L N Q Q Q L P E C K T Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505833 405 45718 S213 P F K P A R G S F V N C G M R
Chicken Gallus gallus XP_415486 379 42675 S206 P S K P G R G S F V N C G M K
Frog Xenopus laevis NP_001084926 375 42497 S203 P T K S S K G S F V N C G M R
Zebra Danio Brachydanio rerio NP_001004627 381 42906 S208 P V K A G K G S F V N C G M R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610543 485 53862 Y211 K A K E G H S Y A N V G L L N
Honey Bee Apis mellifera XP_624203 375 42471 S196 P V K S G K G S H V N V G L L
Nematode Worm Caenorhab. elegans Q10950 378 43008 P208 R S K D G R G P I C N I G L E
Sea Urchin Strong. purpuratus XP_792707 557 62888 S365 P V A K G R G S H V N V G L Y
Poplar Tree Populus trichocarpa XP_002311607 366 41296 T193 K V P N S G E T L V D V G L S
Maize Zea mays NP_001149839 365 41029 V196 D P S K G T L V D V G L S K N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.3 38 87.8 N.A. 88 57.7 N.A. 71.5 71.5 67.2 66.6 N.A. 38.5 47 37.5 42.1
Protein Similarity: 100 85.3 38 90.9 N.A. 92.2 60.3 N.A. 81.7 84.6 83.2 81.8 N.A. 53.4 68.6 55.8 51.5
P-Site Identity: 100 100 0 100 N.A. 80 13.3 N.A. 66.6 80 66.6 66.6 N.A. 13.3 46.6 26.6 46.6
P-Site Similarity: 100 100 0 100 N.A. 86.6 13.3 N.A. 80 93.3 80 80 N.A. 26.6 60 53.3 53.3
Percent
Protein Identity: 43.6 42.5 N.A. N.A. N.A. N.A.
Protein Similarity: 61.9 60.1 N.A. N.A. N.A. N.A.
P-Site Identity: 13.3 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 33.3 13.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 13 7 0 0 0 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 0 57 0 0 0 % C
% Asp: 7 0 0 7 0 0 0 0 7 0 7 0 0 0 0 % D
% Glu: 0 0 0 7 0 0 7 0 0 0 7 0 0 0 7 % E
% Phe: 0 7 0 0 0 0 0 0 44 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 69 7 69 0 0 0 7 7 75 0 0 % G
% His: 0 0 0 0 0 32 0 0 13 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 7 0 0 7 0 0 0 % I
% Lys: 13 0 50 13 0 19 0 0 0 0 0 0 7 7 32 % K
% Leu: 0 0 0 7 0 0 7 0 19 0 0 7 7 32 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 % M
% Asn: 0 0 0 7 7 0 0 0 0 7 69 0 0 0 13 % N
% Pro: 63 7 7 32 0 0 0 7 0 7 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 7 7 0 0 0 0 0 0 0 % Q
% Arg: 7 0 25 0 0 25 0 0 0 0 0 0 0 0 19 % R
% Ser: 0 13 7 13 13 0 7 63 0 0 0 0 7 0 7 % S
% Thr: 7 32 0 0 0 7 0 7 0 0 0 0 0 7 0 % T
% Val: 0 32 0 0 0 0 0 7 0 75 7 19 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 13 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _