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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C9orf114 All Species: 33.64
Human Site: T124 Identified Species: 49.33
UniProt: Q5T280 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T280 NP_057474.2 376 42009 T124 E E G Q D A K T V E G E F T G
Chimpanzee Pan troglodytes XP_520300 437 48483 T185 E E G Q D A K T V E G E F T G
Rhesus Macaque Macaca mulatta XP_001119071 143 15934
Dog Lupus familis XP_851147 396 44060 T124 E E G Q D V K T V E G E F R G
Cat Felis silvestris
Mouse Mus musculus Q3UHX9 385 42939 S125 E E G Q D T K S V E G E F R G
Rat Rattus norvegicus NP_001040575 242 26174 D31 A F F P K H Q D L Q F A G I L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505833 405 45718 S132 E E G E D S K S V E G K F D G
Chicken Gallus gallus XP_415486 379 42675 S125 E H G E D A K S V E G E F E G
Frog Xenopus laevis NP_001084926 375 42497 S122 E T G E G S K S V E G D F E G
Zebra Danio Brachydanio rerio NP_001004627 381 42906 S127 E L G E D A K S V E G E F K G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610543 485 53862 E130 R E T K R S Y E A D G E G S S
Honey Bee Apis mellifera XP_624203 375 42471 S112 D K G E I I E S E K K K I K N
Nematode Worm Caenorhab. elegans Q10950 378 43008 Y123 D E A V N A Y Y N G T W Q G N
Sea Urchin Strong. purpuratus XP_792707 557 62888 N284 S G A A A R E N T D G V Y S G
Poplar Tree Populus trichocarpa XP_002311607 366 41296 T113 N Y E K E D R T L T T D N Y S
Maize Zea mays NP_001149839 365 41029 V108 T V F R I D E V V V F D S T P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.3 38 87.8 N.A. 88 57.7 N.A. 71.5 71.5 67.2 66.6 N.A. 38.5 47 37.5 42.1
Protein Similarity: 100 85.3 38 90.9 N.A. 92.2 60.3 N.A. 81.7 84.6 83.2 81.8 N.A. 53.4 68.6 55.8 51.5
P-Site Identity: 100 100 0 86.6 N.A. 80 0 N.A. 66.6 73.3 53.3 73.3 N.A. 20 6.6 13.3 13.3
P-Site Similarity: 100 100 0 86.6 N.A. 86.6 20 N.A. 93.3 86.6 80 86.6 N.A. 46.6 53.3 26.6 40
Percent
Protein Identity: 43.6 42.5 N.A. N.A. N.A. N.A.
Protein Similarity: 61.9 60.1 N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 40 33.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 13 7 7 32 0 0 7 0 0 7 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 0 0 44 13 0 7 0 13 0 19 0 7 0 % D
% Glu: 50 44 7 32 7 0 19 7 7 50 0 44 0 13 0 % E
% Phe: 0 7 13 0 0 0 0 0 0 0 13 0 50 0 0 % F
% Gly: 0 7 57 0 7 0 0 0 0 7 63 0 13 7 57 % G
% His: 0 7 0 0 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 13 7 0 0 0 0 0 0 7 7 0 % I
% Lys: 0 7 0 13 7 0 50 0 0 7 7 13 0 13 0 % K
% Leu: 0 7 0 0 0 0 0 0 13 0 0 0 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 7 0 0 7 7 0 0 0 7 0 13 % N
% Pro: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 7 % P
% Gln: 0 0 0 25 0 0 7 0 0 7 0 0 7 0 0 % Q
% Arg: 7 0 0 7 7 7 7 0 0 0 0 0 0 13 0 % R
% Ser: 7 0 0 0 0 19 0 38 0 0 0 0 7 13 13 % S
% Thr: 7 7 7 0 0 7 0 25 7 7 13 0 0 19 0 % T
% Val: 0 7 0 7 0 7 0 7 57 7 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 7 0 0 0 0 13 7 0 0 0 0 7 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _