Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C9orf114 All Species: 12.73
Human Site: T130 Identified Species: 18.67
UniProt: Q5T280 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T280 NP_057474.2 376 42009 T130 K T V E G E F T G V G K K G Q
Chimpanzee Pan troglodytes XP_520300 437 48483 T191 K T V E G E F T G V G K K G Q
Rhesus Macaque Macaca mulatta XP_001119071 143 15934
Dog Lupus familis XP_851147 396 44060 R130 K T V E G E F R G V G K K G Q
Cat Felis silvestris
Mouse Mus musculus Q3UHX9 385 42939 R131 K S V E G E F R G V G K K G Q
Rat Rattus norvegicus NP_001040575 242 26174 I37 Q D L Q F A G I L N P L D S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505833 405 45718 D138 K S V E G K F D G I G K K G R
Chicken Gallus gallus XP_415486 379 42675 E131 K S V E G E F E G I G K R G K
Frog Xenopus laevis NP_001084926 375 42497 E128 K S V E G D F E G V G K K G Q
Zebra Danio Brachydanio rerio NP_001004627 381 42906 K133 K S V E G E F K G V G K K G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610543 485 53862 S136 Y E A D G E G S S T G T V R S
Honey Bee Apis mellifera XP_624203 375 42471 K118 E S E K K K I K N D E I L G E
Nematode Worm Caenorhab. elegans Q10950 378 43008 G129 Y Y N G T W Q G N L I P A E T
Sea Urchin Strong. purpuratus XP_792707 557 62888 S290 E N T D G V Y S G I G K K G N
Poplar Tree Populus trichocarpa XP_002311607 366 41296 Y119 R T L T T D N Y S D E N E S G
Maize Zea mays NP_001149839 365 41029 T114 E V V V F D S T P A A E N G S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.3 38 87.8 N.A. 88 57.7 N.A. 71.5 71.5 67.2 66.6 N.A. 38.5 47 37.5 42.1
Protein Similarity: 100 85.3 38 90.9 N.A. 92.2 60.3 N.A. 81.7 84.6 83.2 81.8 N.A. 53.4 68.6 55.8 51.5
P-Site Identity: 100 100 0 93.3 N.A. 86.6 0 N.A. 66.6 66.6 80 86.6 N.A. 20 6.6 0 40
P-Site Similarity: 100 100 0 93.3 N.A. 93.3 20 N.A. 93.3 93.3 93.3 93.3 N.A. 33.3 40 6.6 73.3
Percent
Protein Identity: 43.6 42.5 N.A. N.A. N.A. N.A.
Protein Similarity: 61.9 60.1 N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 20 N.A. N.A. N.A. N.A.
P-Site Similarity: 33.3 40 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 7 0 0 0 7 7 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 13 0 19 0 7 0 13 0 0 7 0 0 % D
% Glu: 19 7 7 50 0 44 0 13 0 0 13 7 7 7 7 % E
% Phe: 0 0 0 0 13 0 50 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 63 0 13 7 57 0 63 0 0 69 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 7 0 19 7 7 0 0 0 % I
% Lys: 50 0 0 7 7 13 0 13 0 0 0 57 50 0 7 % K
% Leu: 0 0 13 0 0 0 0 0 7 7 0 7 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 0 0 0 7 0 13 7 0 7 7 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 7 0 7 7 0 0 7 % P
% Gln: 7 0 0 7 0 0 7 0 0 0 0 0 0 0 38 % Q
% Arg: 7 0 0 0 0 0 0 13 0 0 0 0 7 7 7 % R
% Ser: 0 38 0 0 0 0 7 13 13 0 0 0 0 13 13 % S
% Thr: 0 25 7 7 13 0 0 19 0 7 0 7 0 0 7 % T
% Val: 0 7 57 7 0 7 0 0 0 38 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 7 0 0 0 0 7 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _