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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C9orf114 All Species: 35.45
Human Site: Y73 Identified Species: 52
UniProt: Q5T280 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T280 NP_057474.2 376 42009 Y73 K E D R G R P Y T L S V A L P
Chimpanzee Pan troglodytes XP_520300 437 48483 Y134 K E D R G R P Y T L S V A L P
Rhesus Macaque Macaca mulatta XP_001119071 143 15934
Dog Lupus familis XP_851147 396 44060 Y73 R E D Q G R P Y T L S V A L P
Cat Felis silvestris
Mouse Mus musculus Q3UHX9 385 42939 Y74 R S N Q G R P Y T L S V A L P
Rat Rattus norvegicus NP_001040575 242 26174
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505833 405 45718 Y81 R N D R G R P Y T L S V A L P
Chicken Gallus gallus XP_415486 379 42675 Y74 E E D K G R H Y T L S V A L P
Frog Xenopus laevis NP_001084926 375 42497 Y71 K S P K G R Q Y T V S V A L P
Zebra Danio Brachydanio rerio NP_001004627 381 42906 Y76 K E S K G R L Y T V S V A L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610543 485 53862 S72 A K D K P N P S T L S I A V P
Honey Bee Apis mellifera XP_624203 375 42471 S61 H F E K K D I S T I S I A V P
Nematode Worm Caenorhab. elegans Q10950 378 43008 F66 K V D H T P P F T I S I A V P
Sea Urchin Strong. purpuratus XP_792707 557 62888 W232 L A E N G R P W T L S I A L P
Poplar Tree Populus trichocarpa XP_002311607 366 41296 P59 V I K A K E I P T V S V A I S
Maize Zea mays NP_001149839 365 41029 P69 E E K K K L K P T V S I A V A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.3 38 87.8 N.A. 88 57.7 N.A. 71.5 71.5 67.2 66.6 N.A. 38.5 47 37.5 42.1
Protein Similarity: 100 85.3 38 90.9 N.A. 92.2 60.3 N.A. 81.7 84.6 83.2 81.8 N.A. 53.4 68.6 55.8 51.5
P-Site Identity: 100 100 0 86.6 N.A. 73.3 0 N.A. 86.6 80 66.6 73.3 N.A. 46.6 26.6 46.6 60
P-Site Similarity: 100 100 0 100 N.A. 93.3 0 N.A. 93.3 93.3 80 86.6 N.A. 73.3 60 73.3 80
Percent
Protein Identity: 43.6 42.5 N.A. N.A. N.A. N.A.
Protein Similarity: 61.9 60.1 N.A. N.A. N.A. N.A.
P-Site Identity: 26.6 26.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 40 60 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 7 0 0 0 0 0 0 0 0 88 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 44 0 0 7 0 0 0 0 0 0 0 0 0 % D
% Glu: 13 38 13 0 0 7 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 57 0 0 0 0 0 0 0 0 0 0 % G
% His: 7 0 0 7 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 13 0 0 13 0 32 0 7 0 % I
% Lys: 32 7 13 38 19 0 7 0 0 0 0 0 0 0 0 % K
% Leu: 7 0 0 0 0 7 7 0 0 50 0 0 0 57 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 7 0 7 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 7 0 7 7 50 13 0 0 0 0 0 0 75 % P
% Gln: 0 0 0 13 0 0 7 0 0 0 0 0 0 0 0 % Q
% Arg: 19 0 0 19 0 57 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 13 7 0 0 0 0 13 0 0 88 0 0 0 7 % S
% Thr: 0 0 0 0 7 0 0 0 88 0 0 0 0 0 0 % T
% Val: 7 7 0 0 0 0 0 0 0 25 0 57 0 25 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _