KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNYL2
All Species:
2.42
Human Site:
T139
Identified Species:
4.85
UniProt:
Q5T2Q4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T2Q4
XP_374787
361
41278
T139
I
A
S
Q
P
H
L
T
M
T
L
K
S
C
D
Chimpanzee
Pan troglodytes
XP_001153756
364
41862
H138
D
S
T
A
S
Q
P
H
L
T
M
T
L
K
S
Rhesus Macaque
Macaca mulatta
XP_001095265
360
41259
H138
D
S
T
A
S
Q
P
H
L
T
M
T
L
K
S
Dog
Lupus familis
XP_545613
363
41061
N139
D
S
T
V
S
Q
P
N
L
R
T
T
I
K
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGU5
341
39376
Y118
V
S
Q
P
N
L
K
Y
T
I
K
C
V
A
L
Rat
Rattus norvegicus
XP_237211
436
48385
R212
S
N
P
S
D
H
P
R
A
S
T
I
F
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516510
287
33166
A74
T
I
K
C
V
T
L
A
I
Y
Y
H
I
K
N
Chicken
Gallus gallus
XP_421948
326
37625
I114
I
K
C
V
T
L
A
I
F
Y
H
I
K
N
R
Frog
Xenopus laevis
Q6NRF4
343
39306
N119
D
S
T
V
S
Q
P
N
L
R
S
T
I
K
C
Zebra Danio
Brachydanio rerio
Q08CI4
339
38765
T124
K
S
T
I
K
C
V
T
L
A
I
Y
Y
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609519
406
45054
N179
D
S
T
V
S
Q
P
N
L
K
N
T
V
K
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34624
357
41488
N137
V
S
Q
P
H
L
K
N
T
I
K
C
I
S
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
88.3
60
N.A.
51.7
36.4
N.A.
43.7
51.2
54.2
51.7
N.A.
40.8
N.A.
36
N.A.
Protein Similarity:
100
93.9
91.9
75.7
N.A.
66.4
50.2
N.A.
60.1
68.4
70.6
70
N.A.
58.1
N.A.
57.6
N.A.
P-Site Identity:
100
6.6
6.6
0
N.A.
0
6.6
N.A.
6.6
6.6
0
6.6
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
33.3
33.3
20
N.A.
13.3
13.3
N.A.
20
6.6
20
40
N.A.
20
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
17
0
0
9
9
9
9
0
0
0
9
0
% A
% Cys:
0
0
9
9
0
9
0
0
0
0
0
17
0
9
25
% C
% Asp:
42
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
17
0
17
0
0
9
9
0
9
0
% H
% Ile:
17
9
0
9
0
0
0
9
9
17
9
17
34
0
9
% I
% Lys:
9
9
9
0
9
0
17
0
0
9
17
9
9
50
0
% K
% Leu:
0
0
0
0
0
25
17
0
50
0
9
0
17
9
17
% L
% Met:
0
0
0
0
0
0
0
0
9
0
17
0
0
0
0
% M
% Asn:
0
9
0
0
9
0
0
34
0
0
9
0
0
9
9
% N
% Pro:
0
0
9
17
9
0
50
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
17
9
0
42
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
17
0
0
0
0
9
% R
% Ser:
9
67
9
9
42
0
0
0
0
9
9
0
9
9
25
% S
% Thr:
9
0
50
0
9
9
0
17
17
25
17
42
0
0
0
% T
% Val:
17
0
0
34
9
0
9
0
0
0
0
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
17
9
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _