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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDSS1 All Species: 11.21
Human Site: S84 Identified Species: 17.62
UniProt: Q5T2R2 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T2R2 NP_055132.2 415 46261 S84 F H H T T P D S K T H S G E K
Chimpanzee Pan troglodytes XP_507706 415 46302 S84 F H H T T P D S K T H S G E K
Rhesus Macaque Macaca mulatta XP_001102166 415 46267 S84 F H H T T P D S K T H S G E K
Dog Lupus familis XP_849908 365 40815 K62 G L Y E D I R K E L L I S T T
Cat Felis silvestris
Mouse Mus musculus Q33DR2 409 45876 S82 C S C R Q T Q S G E K Y S D P
Rat Rattus norvegicus Q5U2R1 401 44276 Q84 E L S N V A M Q V R K L V G T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506831 398 43655 L81 K Y T D P F K L G R R D L K N
Chicken Gallus gallus XP_418592 366 41291 K63 N L Y E D I K K E L L V S T A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001017656 411 45908 L88 S L H S D A K L K D P F S L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733425 436 48954 P102 S S V H T Q Q P A G P V R E F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_491588 393 42985 Y81 N L G R M T H Y Y F Q Q G G K
Sea Urchin Strong. purpuratus XP_781598 300 33712
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P34802 371 40156 Q68 T K E D N L R Q S E P S S F D
Baker's Yeast Sacchar. cerevisiae P18900 473 52541 S95 P L L V L L L S R A L S E I P
Red Bread Mold Neurospora crassa Q7S565 449 48454 I98 M K F L T G N I R K L L G S G
Conservation
Percent
Protein Identity: 100 97.3 96.8 80.4 N.A. 82.8 21.4 N.A. 77.1 71.5 N.A. 62.1 N.A. 46.5 N.A. 35.6 42.8
Protein Similarity: 100 98.5 97.3 84.3 N.A. 87.9 40.2 N.A. 85 80.2 N.A. 76.6 N.A. 65.3 N.A. 54.9 59.5
P-Site Identity: 100 100 100 0 N.A. 6.6 0 N.A. 0 0 N.A. 13.3 N.A. 13.3 N.A. 13.3 0
P-Site Similarity: 100 100 100 13.3 N.A. 13.3 0 N.A. 13.3 13.3 N.A. 20 N.A. 13.3 N.A. 13.3 0
Percent
Protein Identity: N.A. N.A. N.A. 21.4 27 35.8
Protein Similarity: N.A. N.A. N.A. 38 43.5 52.7
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. 6.6 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 14 0 0 7 7 0 0 0 0 7 % A
% Cys: 7 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 14 20 0 20 0 0 7 0 7 0 7 7 % D
% Glu: 7 0 7 14 0 0 0 0 14 14 0 0 7 27 0 % E
% Phe: 20 0 7 0 0 7 0 0 0 7 0 7 0 7 7 % F
% Gly: 7 0 7 0 0 7 0 0 14 7 0 0 34 14 7 % G
% His: 0 20 27 7 0 0 7 0 0 0 20 0 0 0 0 % H
% Ile: 0 0 0 0 0 14 0 7 0 0 0 7 0 7 0 % I
% Lys: 7 14 0 0 0 0 20 14 27 7 14 0 0 7 27 % K
% Leu: 0 40 7 7 7 14 7 14 0 14 27 14 7 7 0 % L
% Met: 7 0 0 0 7 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 14 0 0 7 7 0 7 0 0 0 0 0 0 0 7 % N
% Pro: 7 0 0 0 7 20 0 7 0 0 20 0 0 0 14 % P
% Gln: 0 0 0 0 7 7 14 14 0 0 7 7 0 0 0 % Q
% Arg: 0 0 0 14 0 0 14 0 14 14 7 0 7 0 0 % R
% Ser: 14 14 7 7 0 0 0 34 7 0 0 34 34 7 0 % S
% Thr: 7 0 7 20 34 14 0 0 0 20 0 0 0 14 14 % T
% Val: 0 0 7 7 7 0 0 0 7 0 0 14 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 14 0 0 0 0 7 7 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _