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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDZK1
All Species:
15.45
Human Site:
T506
Identified Species:
42.5
UniProt:
Q5T2W1
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T2W1
NP_002605.2
519
57129
T506
A
K
E
R
A
H
S
T
A
S
H
S
S
S
N
Chimpanzee
Pan troglodytes
XP_001165411
571
61107
S460
L
E
D
T
S
V
P
S
V
P
L
G
S
R
Q
Rhesus Macaque
Macaca mulatta
XP_001088569
519
56977
T506
A
K
E
R
A
H
S
T
A
S
R
S
S
S
N
Dog
Lupus familis
XP_533031
519
57061
T506
A
K
E
R
A
H
S
T
A
S
H
S
S
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIL4
519
56480
T506
A
K
D
R
T
L
S
T
A
S
H
S
S
S
N
Rat
Rattus norvegicus
Q9JJ40
523
56781
R506
S
S
H
P
A
R
D
R
T
L
S
A
A
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520647
469
50011
P456
A
D
L
P
I
C
E
P
L
D
A
P
R
S
F
Chicken
Gallus gallus
Q5ZM14
333
35786
M321
T
S
K
R
A
P
Q
M
D
W
S
K
K
N
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001122142
552
58882
T522
K
D
I
E
K
P
A
T
P
P
A
P
T
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.1
96.9
87
N.A.
78.4
77.6
N.A.
53.1
28.5
N.A.
44
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
35.9
98.2
92.6
N.A.
86.5
85.2
N.A.
67.4
38.9
N.A.
60.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
100
N.A.
80
13.3
N.A.
13.3
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
93.3
100
N.A.
86.6
40
N.A.
13.3
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
56
0
0
0
56
0
12
0
45
0
23
12
12
0
0
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
23
23
0
0
0
12
0
12
12
0
0
0
0
0
% D
% Glu:
0
12
34
12
0
0
12
0
0
0
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% G
% His:
0
0
12
0
0
34
0
0
0
0
34
0
0
0
12
% H
% Ile:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
45
12
0
12
0
0
0
0
0
0
12
12
0
0
% K
% Leu:
12
0
12
0
0
12
0
0
12
12
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
45
% N
% Pro:
0
0
0
23
0
23
12
12
12
23
0
23
0
0
0
% P
% Gln:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
12
% Q
% Arg:
0
0
0
56
0
12
0
12
0
0
12
0
12
23
0
% R
% Ser:
12
23
0
0
12
0
45
12
0
45
23
45
56
67
12
% S
% Thr:
12
0
0
12
12
0
0
56
12
0
0
0
12
0
0
% T
% Val:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _