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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM63B
All Species:
9.09
Human Site:
Y419
Identified Species:
25
UniProt:
Q5T3F8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T3F8
NP_060896.1
832
94958
Y419
A
P
D
P
Q
N
I
Y
W
E
H
L
S
I
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089796
853
97098
C455
A
A
D
P
E
D
I
C
W
K
N
L
S
I
Q
Dog
Lupus familis
XP_852005
661
75291
N289
S
Y
A
P
D
P
Q
N
I
Y
W
E
H
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3TWI9
832
94757
Y419
A
P
D
P
Q
N
I
Y
W
E
H
L
S
I
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512688
801
91795
C409
A
T
Y
P
E
D
I
C
W
K
N
L
S
I
Q
Chicken
Gallus gallus
XP_419493
838
95899
Y434
A
P
D
P
Q
N
I
Y
W
E
H
L
S
I
R
Frog
Xenopus laevis
NP_001088752
803
91863
C409
A
T
Y
P
E
N
I
C
W
G
N
L
S
L
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392828
767
85105
F388
A
P
T
P
S
D
I
F
W
E
N
L
S
I
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785977
734
83832
K362
V
T
D
Y
T
T
L
K
T
G
P
P
T
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
50
70.7
N.A.
98.1
N.A.
N.A.
56
89.8
54.2
N.A.
N.A.
N.A.
34.7
N.A.
39
Protein Similarity:
100
N.A.
66.2
72.8
N.A.
98.9
N.A.
N.A.
73.8
93.7
71
N.A.
N.A.
N.A.
53.4
N.A.
56.9
P-Site Identity:
100
N.A.
53.3
6.6
N.A.
100
N.A.
N.A.
46.6
100
46.6
N.A.
N.A.
N.A.
60
N.A.
6.6
P-Site Similarity:
100
N.A.
86.6
20
N.A.
100
N.A.
N.A.
80
100
73.3
N.A.
N.A.
N.A.
80
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
78
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% C
% Asp:
0
0
56
0
12
34
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
34
0
0
0
0
45
0
12
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
34
0
12
0
0
% H
% Ile:
0
0
0
0
0
0
78
0
12
0
0
0
0
67
0
% I
% Lys:
0
0
0
0
0
0
0
12
0
23
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
12
0
0
0
0
78
0
23
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
45
0
12
0
0
45
0
0
0
0
% N
% Pro:
0
45
0
89
0
12
0
0
0
0
12
12
0
0
12
% P
% Gln:
0
0
0
0
34
0
12
0
0
0
0
0
0
0
34
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% R
% Ser:
12
0
0
0
12
0
0
0
0
0
0
0
78
0
23
% S
% Thr:
0
34
12
0
12
12
0
0
12
0
0
0
12
0
0
% T
% Val:
12
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
78
0
12
0
0
0
0
% W
% Tyr:
0
12
23
12
0
0
0
34
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _