KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM63B
All Species:
4.55
Human Site:
Y616
Identified Species:
12.5
UniProt:
Q5T3F8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T3F8
NP_060896.1
832
94958
Y616
N
V
K
R
H
Q
A
Y
E
F
Q
F
G
A
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089796
853
97098
D641
I
M
A
K
T
A
A
D
R
R
N
V
K
Q
N
Dog
Lupus familis
XP_852005
661
75291
G452
V
I
A
S
A
F
I
G
N
A
M
D
L
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3TWI9
832
94757
Y616
N
V
K
R
H
Q
A
Y
E
F
Q
F
G
A
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512688
801
91795
K591
T
I
R
M
V
T
A
K
T
A
A
D
Q
R
N
Chicken
Gallus gallus
XP_419493
838
95899
H628
E
R
R
N
V
K
R
H
Q
A
Y
E
F
Q
F
Frog
Xenopus laevis
NP_001088752
803
91863
I582
L
M
R
L
P
G
L
I
L
Y
T
I
R
M
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392828
767
85105
A557
L
V
R
F
P
E
L
A
L
Y
T
F
R
L
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785977
734
83832
I525
S
L
K
S
V
A
E
I
K
M
R
W
G
C
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
50
70.7
N.A.
98.1
N.A.
N.A.
56
89.8
54.2
N.A.
N.A.
N.A.
34.7
N.A.
39
Protein Similarity:
100
N.A.
66.2
72.8
N.A.
98.9
N.A.
N.A.
73.8
93.7
71
N.A.
N.A.
N.A.
53.4
N.A.
56.9
P-Site Identity:
100
N.A.
6.6
0
N.A.
100
N.A.
N.A.
6.6
0
0
N.A.
N.A.
N.A.
13.3
N.A.
13.3
P-Site Similarity:
100
N.A.
20
6.6
N.A.
100
N.A.
N.A.
20
26.6
20
N.A.
N.A.
N.A.
33.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
23
0
12
23
45
12
0
34
12
0
0
23
23
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
0
23
0
0
0
% D
% Glu:
12
0
0
0
0
12
12
0
23
0
0
12
0
0
0
% E
% Phe:
0
0
0
12
0
12
0
0
0
23
0
34
12
0
12
% F
% Gly:
0
0
0
0
0
12
0
12
0
0
0
0
34
0
0
% G
% His:
0
0
0
0
23
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
12
23
0
0
0
0
12
23
0
0
0
12
0
0
23
% I
% Lys:
0
0
34
12
0
12
0
12
12
0
0
0
12
0
0
% K
% Leu:
23
12
0
12
0
0
23
0
23
0
0
0
12
23
0
% L
% Met:
0
23
0
12
0
0
0
0
0
12
12
0
0
12
0
% M
% Asn:
23
0
0
12
0
0
0
0
12
0
12
0
0
0
23
% N
% Pro:
0
0
0
0
23
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
23
0
0
12
0
23
0
12
23
0
% Q
% Arg:
0
12
45
23
0
0
12
0
12
12
12
0
23
12
12
% R
% Ser:
12
0
0
23
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
12
0
0
0
12
12
0
0
12
0
23
0
0
0
0
% T
% Val:
12
34
0
0
34
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
23
0
23
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _