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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECTD3
All Species:
22.73
Human Site:
S251
Identified Species:
83.33
UniProt:
Q5T447
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T447
NP_078878.3
861
97113
S251
V
E
S
I
D
V
S
S
Y
T
E
E
F
N
V
Chimpanzee
Pan troglodytes
XP_513128
810
91321
S251
V
E
S
I
D
V
S
S
Y
T
E
E
F
N
V
Rhesus Macaque
Macaca mulatta
XP_001100268
861
97080
S251
V
E
S
I
D
V
S
S
Y
T
E
E
F
N
V
Dog
Lupus familis
XP_539635
861
97254
S251
V
E
S
I
D
V
S
S
Y
T
E
E
F
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3U487
861
97329
S251
V
E
S
I
D
V
S
S
Y
T
E
E
F
N
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422429
845
96493
S235
V
D
S
I
D
V
S
S
Y
T
E
D
F
N
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
V206
G
R
P
L
S
C
L
V
D
E
N
T
P
I
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
99.7
98.3
N.A.
97.7
N.A.
N.A.
N.A.
79.5
N.A.
20.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.9
100
99.3
N.A.
98.4
N.A.
N.A.
N.A.
88.8
N.A.
37.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
86.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
100
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
86
0
0
0
15
0
0
15
0
0
0
% D
% Glu:
0
72
0
0
0
0
0
0
0
15
86
72
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
86
0
0
% F
% Gly:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
86
0
0
0
0
0
0
0
0
0
15
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
15
0
0
15
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
15
0
0
86
0
% N
% Pro:
0
0
15
0
0
0
0
0
0
0
0
0
15
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
86
0
15
0
86
86
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
86
0
15
0
0
0
% T
% Val:
86
0
0
0
0
86
0
15
0
0
0
0
0
0
86
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
86
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _