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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CERCAM All Species: 21.52
Human Site: S490 Identified Species: 39.44
UniProt: Q5T4B2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T4B2 NP_057258.3 595 67592 S490 G A R K L L A S Q P L R R M L
Chimpanzee Pan troglodytes XP_001157210 595 67421 S490 G A R K L L A S Q P L R C M L
Rhesus Macaque Macaca mulatta XP_001111820 595 67356 S490 G A R K L L A S Q P L R R M L
Dog Lupus familis XP_851283 595 67766 S490 G A R K L L A S Q P L H R M L
Cat Felis silvestris
Mouse Mus musculus A3KGW5 592 67654 S487 G A R K L L A S Q P L H R M L
Rat Rattus norvegicus Q5U309 572 65205 S467 G A R K L L A S Q P L H R M L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516534 431 48397 E338 G R M L P V D E F L P I M Y D
Chicken Gallus gallus XP_422290 627 72474 A514 G A Q K L I G A E P F S K M L
Frog Xenopus laevis Q5U483 611 71588 A501 G A R K L L N A E P L G K M L
Zebra Danio Brachydanio rerio A5PMF6 604 70813 A494 G A Q K L L R A E P L K K M L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IPK4 612 71131 A502 G A L K L L A A K P L D K L I
Honey Bee Apis mellifera XP_397154 552 64723 A453 E S K Y L V H A A Y S Y W T L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783019 624 72066 Q484 G A K K L L A Q E P L G K M V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 96.9 90 N.A. 83.5 78.1 N.A. 51.4 51.5 53.3 51.3 N.A. 39.2 36.8 N.A. 42.9
Protein Similarity: 100 98.8 98.4 93.6 N.A. 89.9 84 N.A. 61 69.5 69.2 68.5 N.A. 57.8 56.4 N.A. 61.7
P-Site Identity: 100 93.3 100 93.3 N.A. 93.3 93.3 N.A. 6.6 46.6 66.6 60 N.A. 53.3 13.3 N.A. 60
P-Site Similarity: 100 93.3 100 93.3 N.A. 93.3 93.3 N.A. 13.3 80 86.6 93.3 N.A. 86.6 40 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 85 0 0 0 0 62 39 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 8 % D
% Glu: 8 0 0 0 0 0 0 8 31 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % F
% Gly: 93 0 0 0 0 0 8 0 0 0 0 16 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 24 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 8 % I
% Lys: 0 0 16 85 0 0 0 0 8 0 0 8 39 0 0 % K
% Leu: 0 0 8 8 93 77 0 0 0 8 77 0 0 8 77 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 8 77 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 85 8 0 0 0 0 % P
% Gln: 0 0 16 0 0 0 0 8 47 0 0 0 0 0 0 % Q
% Arg: 0 8 54 0 0 0 8 0 0 0 0 24 39 0 0 % R
% Ser: 0 8 0 0 0 0 0 47 0 0 8 8 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % T
% Val: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 8 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _