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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CERCAM All Species: 38.18
Human Site: S547 Identified Species: 70
UniProt: Q5T4B2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T4B2 NP_057258.3 595 67592 S547 A G D A E W L S D T E T S S P
Chimpanzee Pan troglodytes XP_001157210 595 67421 S547 A G D A E W L S D T E T S S P
Rhesus Macaque Macaca mulatta XP_001111820 595 67356 S547 A G D A E W L S D T E T S S P
Dog Lupus familis XP_851283 595 67766 S547 A G D A E W L S D T E T S S P
Cat Felis silvestris
Mouse Mus musculus A3KGW5 592 67654 S544 S G D A E W L S D T E T S S P
Rat Rattus norvegicus Q5U309 572 65205 S524 A G D T E W L S D T E T S S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516534 431 48397 D385 G D A Q W L S D T E T S T I W
Chicken Gallus gallus XP_422290 627 72474 S571 T G Q P G Y L S D T E T S T I
Frog Xenopus laevis Q5U483 611 71588 S558 T G D K G Y I S D T E T S V L
Zebra Danio Brachydanio rerio A5PMF6 604 70813 S551 T G D Q G Y I S D T E T S S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IPK4 612 71131 S559 T G E S G Y I S D T E D S Q Q
Honey Bee Apis mellifera XP_397154 552 64723 P505 K D W K I Y Y P K R N L I I L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783019 624 72066 S541 T G E K K Y F S D T E T S S I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 96.9 90 N.A. 83.5 78.1 N.A. 51.4 51.5 53.3 51.3 N.A. 39.2 36.8 N.A. 42.9
Protein Similarity: 100 98.8 98.4 93.6 N.A. 89.9 84 N.A. 61 69.5 69.2 68.5 N.A. 57.8 56.4 N.A. 61.7
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 0 53.3 53.3 60 N.A. 40 0 N.A. 53.3
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 13.3 66.6 66.6 73.3 N.A. 66.6 6.6 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 39 0 8 39 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 16 62 0 0 0 0 8 85 0 0 8 0 0 0 % D
% Glu: 0 0 16 0 47 0 0 0 0 8 85 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 8 85 0 0 31 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 24 0 0 0 0 0 8 16 16 % I
% Lys: 8 0 0 24 8 0 0 0 8 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 8 54 0 0 0 0 8 0 0 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 47 % P
% Gln: 0 0 8 16 0 0 0 0 0 0 0 0 0 8 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 8 0 0 8 0 0 8 85 0 0 0 8 85 62 0 % S
% Thr: 39 0 0 8 0 0 0 0 8 85 8 77 8 8 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % V
% Trp: 0 0 8 0 8 47 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 0 47 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _