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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CERCAM All Species: 33.64
Human Site: S553 Identified Species: 61.67
UniProt: Q5T4B2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T4B2 NP_057258.3 595 67592 S553 L S D T E T S S P W D D D S G
Chimpanzee Pan troglodytes XP_001157210 595 67421 S553 L S D T E T S S P W D D D S G
Rhesus Macaque Macaca mulatta XP_001111820 595 67356 S553 L S D T E T S S P W D D D S G
Dog Lupus familis XP_851283 595 67766 S553 L S D T E T S S P W D D D S G
Cat Felis silvestris
Mouse Mus musculus A3KGW5 592 67654 S550 L S D T E T S S P W D D D S G
Rat Rattus norvegicus Q5U309 572 65205 S530 L S D T E T S S P W D D D S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516534 431 48397 I391 S D T E T S T I W D D D S R A
Chicken Gallus gallus XP_422290 627 72474 T577 L S D T E T S T I W D N E T V
Frog Xenopus laevis Q5U483 611 71588 V564 I S D T E T S V L W D N V T Q
Zebra Danio Brachydanio rerio A5PMF6 604 70813 S557 I S D T E T S S V W D N E S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IPK4 612 71131 Q565 I S D T E D S Q Q I S V E T S
Honey Bee Apis mellifera XP_397154 552 64723 I511 Y P K R N L I I L S A N P L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783019 624 72066 S547 F S D T E T S S I W E E L E K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 96.9 90 N.A. 83.5 78.1 N.A. 51.4 51.5 53.3 51.3 N.A. 39.2 36.8 N.A. 42.9
Protein Similarity: 100 98.8 98.4 93.6 N.A. 89.9 84 N.A. 61 69.5 69.2 68.5 N.A. 57.8 56.4 N.A. 61.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 13.3 60 53.3 66.6 N.A. 33.3 0 N.A. 53.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 26.6 86.6 73.3 86.6 N.A. 53.3 6.6 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 85 0 0 8 0 0 0 8 77 54 47 0 0 % D
% Glu: 0 0 0 8 85 0 0 0 0 0 8 8 24 8 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 24 0 0 0 0 0 8 16 16 8 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % K
% Leu: 54 0 0 0 0 8 0 0 16 0 0 0 8 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 31 0 0 0 % N
% Pro: 0 8 0 0 0 0 0 0 47 0 0 0 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 8 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 8 85 0 0 0 8 85 62 0 8 8 0 8 54 8 % S
% Thr: 0 0 8 85 8 77 8 8 0 0 0 0 0 24 0 % T
% Val: 0 0 0 0 0 0 0 8 8 0 0 8 8 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 8 77 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _