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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CERCAM All Species: 11.52
Human Site: S574 Identified Species: 21.11
UniProt: Q5T4B2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T4B2 NP_057258.3 595 67592 S574 G S Q K T L R S P R L D L T G
Chimpanzee Pan troglodytes XP_001157210 595 67421 S574 G S Q K T L R S P R L D L T G
Rhesus Macaque Macaca mulatta XP_001111820 595 67356 S574 G S Q K T L R S P R L D M A G
Dog Lupus familis XP_851283 595 67766 G574 G S H K T L R G P R L D L A G
Cat Felis silvestris
Mouse Mus musculus A3KGW5 592 67654 G571 G S Q K A L R G P H L H L T G
Rat Rattus norvegicus Q5U309 572 65205 G551 G S Q K T L R G P Y L H L A G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516534 431 48397 R412 H K T L K D T R L D G G G S S
Chicken Gallus gallus XP_422290 627 72474 Q598 T H S W K S R Q Q G Q I H S E
Frog Xenopus laevis Q5U483 611 71588 Q585 A K S R K T H Q Q E K L R S E
Zebra Danio Brachydanio rerio A5PMF6 604 70813 E578 A R S R K S R E Q E E L S S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IPK4 612 71131 V586 L K S D R E Q V F D H E Q E F
Honey Bee Apis mellifera XP_397154 552 64723 S532 T G E Q G Y V S D T E N S T I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783019 624 72066 T568 G V A Q T N E T S T D G G N A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 96.9 90 N.A. 83.5 78.1 N.A. 51.4 51.5 53.3 51.3 N.A. 39.2 36.8 N.A. 42.9
Protein Similarity: 100 98.8 98.4 93.6 N.A. 89.9 84 N.A. 61 69.5 69.2 68.5 N.A. 57.8 56.4 N.A. 61.7
P-Site Identity: 100 100 86.6 80 N.A. 73.3 73.3 N.A. 0 6.6 0 6.6 N.A. 0 13.3 N.A. 13.3
P-Site Similarity: 100 100 93.3 80 N.A. 73.3 73.3 N.A. 6.6 13.3 13.3 20 N.A. 13.3 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 8 0 8 0 0 0 0 0 0 0 0 24 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 8 0 0 8 16 8 31 0 0 0 % D
% Glu: 0 0 8 0 0 8 8 8 0 16 16 8 0 8 24 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % F
% Gly: 54 8 0 0 8 0 0 24 0 8 8 16 16 0 47 % G
% His: 8 8 8 0 0 0 8 0 0 8 8 16 8 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % I
% Lys: 0 24 0 47 31 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 8 0 0 8 0 47 0 0 8 0 47 16 39 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 0 8 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 47 0 0 0 0 0 0 % P
% Gln: 0 0 39 16 0 0 8 16 24 0 8 0 8 0 0 % Q
% Arg: 0 8 0 16 8 0 62 8 0 31 0 0 8 0 0 % R
% Ser: 0 47 31 0 0 16 0 31 8 0 0 0 16 31 8 % S
% Thr: 16 0 8 0 47 8 8 8 0 16 0 0 0 31 0 % T
% Val: 0 8 0 0 0 0 8 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _