KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CERCAM
All Species:
19.7
Human Site:
S586
Identified Species:
36.11
UniProt:
Q5T4B2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T4B2
NP_057258.3
595
67592
S586
L
T
G
S
S
G
H
S
L
Q
P
Q
P
R
D
Chimpanzee
Pan troglodytes
XP_001157210
595
67421
S586
L
T
G
S
S
G
H
S
L
Q
P
Q
P
R
D
Rhesus Macaque
Macaca mulatta
XP_001111820
595
67356
S586
M
A
G
S
S
G
H
S
L
Q
P
Q
P
R
D
Dog
Lupus familis
XP_851283
595
67766
S586
L
A
G
S
S
G
H
S
L
H
P
H
P
R
D
Cat
Felis silvestris
Mouse
Mus musculus
A3KGW5
592
67654
S583
L
T
G
S
S
G
H
S
L
H
P
H
H
R
D
Rat
Rattus norvegicus
Q5U309
572
65205
S563
L
A
G
S
S
G
H
S
L
H
P
H
P
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516534
431
48397
R424
G
S
S
G
H
S
L
R
P
T
S
R
D
E
L
Chicken
Gallus gallus
XP_422290
627
72474
D610
H
S
E
A
Q
N
K
D
A
L
P
P
Q
S
S
Frog
Xenopus laevis
Q5U483
611
71588
P597
R
S
E
A
L
N
T
P
S
M
G
S
P
F
D
Zebra Danio
Brachydanio rerio
A5PMF6
604
70813
D590
S
S
E
A
Q
N
T
D
V
L
Q
S
P
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IPK4
612
71131
E598
Q
E
F
K
L
N
P
E
L
K
L
G
E
S
L
Honey Bee
Apis mellifera
XP_397154
552
64723
Q544
S
T
I
I
F
D
H
Q
N
K
S
K
R
E
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783019
624
72066
V580
G
N
A
P
N
E
Q
V
P
P
S
E
G
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
96.9
90
N.A.
83.5
78.1
N.A.
51.4
51.5
53.3
51.3
N.A.
39.2
36.8
N.A.
42.9
Protein Similarity:
100
98.8
98.4
93.6
N.A.
89.9
84
N.A.
61
69.5
69.2
68.5
N.A.
57.8
56.4
N.A.
61.7
P-Site Identity:
100
100
86.6
80
N.A.
80
80
N.A.
0
6.6
13.3
13.3
N.A.
6.6
20
N.A.
0
P-Site Similarity:
100
100
93.3
80
N.A.
80
80
N.A.
13.3
20
26.6
33.3
N.A.
13.3
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
8
24
0
0
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
16
0
0
0
0
8
0
70
% D
% Glu:
0
8
24
0
0
8
0
8
0
0
0
8
8
16
0
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
16
0
47
8
0
47
0
0
0
0
8
8
8
0
0
% G
% His:
8
0
0
0
8
0
54
0
0
24
0
24
8
0
0
% H
% Ile:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
8
0
0
16
0
8
0
0
8
% K
% Leu:
39
0
0
0
16
0
8
0
54
16
8
0
0
8
16
% L
% Met:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
31
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
8
8
16
8
54
8
54
0
0
% P
% Gln:
8
0
0
0
16
0
8
8
0
24
8
24
8
0
0
% Q
% Arg:
8
0
0
0
0
0
0
8
0
0
0
8
8
47
0
% R
% Ser:
16
31
8
47
47
8
0
47
8
0
24
16
0
16
8
% S
% Thr:
0
31
0
0
0
0
16
0
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _