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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CERCAM
All Species:
41.21
Human Site:
Y375
Identified Species:
75.56
UniProt:
Q5T4B2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T4B2
NP_057258.3
595
67592
Y375
G
V
D
L
L
P
G
Y
Q
D
P
Y
S
G
R
Chimpanzee
Pan troglodytes
XP_001157210
595
67421
Y375
G
V
D
L
L
P
G
Y
Q
D
P
Y
S
G
R
Rhesus Macaque
Macaca mulatta
XP_001111820
595
67356
Y375
G
V
D
L
L
P
G
Y
Q
D
P
Y
S
G
R
Dog
Lupus familis
XP_851283
595
67766
Y375
G
V
D
L
L
P
G
Y
Q
D
P
Y
S
G
R
Cat
Felis silvestris
Mouse
Mus musculus
A3KGW5
592
67654
Y372
G
V
D
L
L
P
G
Y
Q
D
P
Y
S
G
H
Rat
Rattus norvegicus
Q5U309
572
65205
Y352
G
V
D
L
L
P
G
Y
Q
D
P
Y
S
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516534
431
48397
W236
F
L
S
H
H
A
V
W
E
E
V
A
A
R
G
Chicken
Gallus gallus
XP_422290
627
72474
Y398
S
I
D
M
L
P
G
Y
R
D
P
Y
S
S
R
Frog
Xenopus laevis
Q5U483
611
71588
Y385
G
I
K
M
L
P
G
Y
K
D
P
Y
H
G
R
Zebra Danio
Brachydanio rerio
A5PMF6
604
70813
Y378
G
I
K
M
L
P
G
Y
S
D
P
Y
H
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IPK4
612
71131
Y388
G
V
R
F
L
P
G
Y
E
D
P
Y
H
H
R
Honey Bee
Apis mellifera
XP_397154
552
64723
E350
A
L
N
Q
S
I
L
E
K
M
G
I
K
I
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783019
624
72066
Y369
G
I
D
M
L
P
G
Y
A
D
P
Y
W
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
96.9
90
N.A.
83.5
78.1
N.A.
51.4
51.5
53.3
51.3
N.A.
39.2
36.8
N.A.
42.9
Protein Similarity:
100
98.8
98.4
93.6
N.A.
89.9
84
N.A.
61
69.5
69.2
68.5
N.A.
57.8
56.4
N.A.
61.7
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
0
66.6
66.6
66.6
N.A.
66.6
0
N.A.
73.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
33.3
86.6
86.6
80
N.A.
73.3
20
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
0
8
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
62
0
0
0
0
0
0
85
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
16
8
0
0
0
0
0
% E
% Phe:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
77
0
0
0
0
0
85
0
0
0
8
0
0
70
8
% G
% His:
0
0
0
8
8
0
0
0
0
0
0
0
24
8
8
% H
% Ile:
0
31
0
0
0
8
0
0
0
0
0
8
0
8
0
% I
% Lys:
0
0
16
0
0
0
0
0
16
0
0
0
8
0
0
% K
% Leu:
0
16
0
47
85
0
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
31
0
0
0
0
0
8
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
85
0
0
0
0
85
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
47
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
8
0
0
0
0
8
77
% R
% Ser:
8
0
8
0
8
0
0
0
8
0
0
0
54
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
54
0
0
0
0
8
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
85
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _