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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CERCAM All Species: 18.18
Human Site: Y49 Identified Species: 33.33
UniProt: Q5T4B2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T4B2 NP_057258.3 595 67592 Y49 A E H S L P H Y L G A L E R L
Chimpanzee Pan troglodytes XP_001157210 595 67421 Y49 A E H S L P H Y L G A L E R L
Rhesus Macaque Macaca mulatta XP_001111820 595 67356 Y49 A E H S L P H Y L G A L E R L
Dog Lupus familis XP_851283 595 67766 Y49 A E H S L P H Y L G A L E R L
Cat Felis silvestris
Mouse Mus musculus A3KGW5 592 67654 Y46 A E H S L P H Y L G A L E R L
Rat Rattus norvegicus Q5U309 572 65205 L27 P D Q L H P I L F T N L R L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516534 431 48397
Chicken Gallus gallus XP_422290 627 72474 F72 A A S A L P H F L G C V E R L
Frog Xenopus laevis Q5U483 611 71588 V59 S E G S L P E V L G A L D R L
Zebra Danio Brachydanio rerio A5PMF6 604 70813 V52 S A H S L P H V L G A I D R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IPK4 612 71131 F48 K A H I L P M F L S Y L E Q Q
Honey Bee Apis mellifera XP_397154 552 64723 F31 K A H T L P Y F L T F L E R L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783019 624 72066 F42 K A H T L P H F F G Y L E R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 96.9 90 N.A. 83.5 78.1 N.A. 51.4 51.5 53.3 51.3 N.A. 39.2 36.8 N.A. 42.9
Protein Similarity: 100 98.8 98.4 93.6 N.A. 89.9 84 N.A. 61 69.5 69.2 68.5 N.A. 57.8 56.4 N.A. 61.7
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. 0 60 66.6 66.6 N.A. 40 53.3 N.A. 60
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 0 80 80 86.6 N.A. 53.3 73.3 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 39 0 8 0 0 0 0 0 0 54 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 0 16 0 0 % D
% Glu: 0 47 0 0 0 0 8 0 0 0 0 0 70 0 0 % E
% Phe: 0 0 0 0 0 0 0 31 16 0 8 0 0 0 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 70 0 0 0 0 0 % G
% His: 0 0 70 0 8 0 62 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 8 0 0 0 0 8 0 0 0 % I
% Lys: 24 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 8 85 0 0 8 77 0 0 77 0 8 77 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 8 0 0 0 0 93 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 8 77 0 % R
% Ser: 16 0 8 54 0 0 0 0 0 8 0 0 0 0 0 % S
% Thr: 0 0 0 16 0 0 0 0 0 16 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 16 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 39 0 0 16 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _