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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC4
All Species:
3.33
Human Site:
S14
Identified Species:
8.15
UniProt:
Q5T4D3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T4D3
NP_001073137.1
741
82991
S14
D
L
D
H
I
L
P
S
S
V
L
P
P
F
W
Chimpanzee
Pan troglodytes
XP_509717
790
88939
C63
Q
R
E
E
K
I
L
C
R
S
P
S
Q
L
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534177
1013
112724
A287
D
L
D
H
I
I
P
A
S
V
L
P
P
F
W
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG19
741
82944
S14
D
L
D
H
I
V
P
S
V
L
P
P
F
W
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416968
790
89162
W14
N
L
D
H
D
I
S
W
F
L
L
P
S
C
W
Frog
Xenopus laevis
Q6DCD5
836
94386
L19
L
L
L
Y
L
N
T
L
G
A
D
F
C
Y
D
Zebra Danio
Brachydanio rerio
NP_001166973
739
83162
L14
Y
W
D
H
H
I
P
L
P
K
L
G
P
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VF81
705
80433
V14
K
A
T
L
H
S
M
V
C
Q
A
I
L
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20144
690
77719
K23
G
D
R
S
P
K
E
K
G
R
S
Q
G
I
R
Sea Urchin
Strong. purpuratus
XP_787838
666
75633
I14
D
I
I
I
N
C
G
I
D
P
V
P
A
F
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
N.A.
68.3
N.A.
90.6
N.A.
N.A.
N.A.
79.7
33.7
68.2
N.A.
37.7
N.A.
36
39.4
Protein Similarity:
100
90.8
N.A.
70.7
N.A.
94.7
N.A.
N.A.
N.A.
87
51.6
81.1
N.A.
55.8
N.A.
53.7
57.3
P-Site Identity:
100
0
N.A.
86.6
N.A.
53.3
N.A.
N.A.
N.A.
40
6.6
33.3
N.A.
0
N.A.
0
20
P-Site Similarity:
100
13.3
N.A.
100
N.A.
73.3
N.A.
N.A.
N.A.
60
26.6
40
N.A.
0
N.A.
0
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
10
0
10
10
0
10
0
10
% A
% Cys:
0
0
0
0
0
10
0
10
10
0
0
0
10
10
0
% C
% Asp:
40
10
50
0
10
0
0
0
10
0
10
0
0
0
10
% D
% Glu:
0
0
10
10
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
10
10
30
0
% F
% Gly:
10
0
0
0
0
0
10
0
20
0
0
10
10
0
0
% G
% His:
0
0
0
50
20
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
10
10
10
30
40
0
10
0
0
0
10
0
10
0
% I
% Lys:
10
0
0
0
10
10
0
10
0
10
0
0
0
0
0
% K
% Leu:
10
50
10
10
10
10
10
20
0
20
40
0
10
20
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
40
0
10
10
20
50
30
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
10
0
10
10
0
0
% Q
% Arg:
0
10
10
0
0
0
0
0
10
10
0
0
0
0
10
% R
% Ser:
0
0
0
10
0
10
10
20
20
10
10
10
10
0
10
% S
% Thr:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
10
0
10
10
20
10
0
0
10
0
% V
% Trp:
0
10
0
0
0
0
0
10
0
0
0
0
0
10
30
% W
% Tyr:
10
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _