KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC4
All Species:
12.12
Human Site:
S195
Identified Species:
29.63
UniProt:
Q5T4D3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T4D3
NP_001073137.1
741
82991
S195
Y
C
K
A
F
R
E
S
N
K
E
G
A
H
S
Chimpanzee
Pan troglodytes
XP_509717
790
88939
S244
Y
C
K
A
F
R
E
S
N
K
E
G
A
H
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534177
1013
112724
S468
Y
C
K
A
F
R
E
S
N
K
E
G
T
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG19
741
82944
T194
Y
C
Q
A
F
K
E
T
G
N
K
E
G
T
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416968
790
89162
N195
Y
C
K
A
F
R
E
N
K
E
G
H
N
F
S
Frog
Xenopus laevis
Q6DCD5
836
94386
Y199
V
L
A
V
S
A
V
Y
D
V
F
V
F
H
K
Zebra Danio
Brachydanio rerio
NP_001166973
739
83162
G195
Y
C
K
A
F
Q
V
G
G
D
K
K
F
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VF81
705
80433
L188
L
G
P
Q
T
G
G
L
I
M
L
L
T
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20144
690
77719
V197
R
E
I
N
C
K
F
V
L
L
V
I
L
S
T
Sea Urchin
Strong. purpuratus
XP_787838
666
75633
E187
Q
L
A
V
H
S
P
E
L
R
W
L
R
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
N.A.
68.3
N.A.
90.6
N.A.
N.A.
N.A.
79.7
33.7
68.2
N.A.
37.7
N.A.
36
39.4
Protein Similarity:
100
90.8
N.A.
70.7
N.A.
94.7
N.A.
N.A.
N.A.
87
51.6
81.1
N.A.
55.8
N.A.
53.7
57.3
P-Site Identity:
100
100
N.A.
93.3
N.A.
33.3
N.A.
N.A.
N.A.
53.3
6.6
33.3
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
60
N.A.
N.A.
N.A.
66.6
13.3
46.6
N.A.
0
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
60
0
10
0
0
0
0
0
0
20
10
0
% A
% Cys:
0
60
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
50
10
0
10
30
10
0
0
0
% E
% Phe:
0
0
0
0
60
0
10
0
0
0
10
0
20
10
0
% F
% Gly:
0
10
0
0
0
10
10
10
20
0
10
30
10
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
10
0
40
10
% H
% Ile:
0
0
10
0
0
0
0
0
10
0
0
10
0
0
0
% I
% Lys:
0
0
50
0
0
20
0
0
10
30
20
10
0
0
10
% K
% Leu:
10
20
0
0
0
0
0
10
20
10
10
20
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
30
10
0
0
10
0
0
% N
% Pro:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
10
10
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
40
0
0
0
10
0
0
10
10
0
% R
% Ser:
0
0
0
0
10
10
0
30
0
0
0
0
0
20
40
% S
% Thr:
0
0
0
0
10
0
0
10
0
0
0
0
20
10
10
% T
% Val:
10
0
0
20
0
0
20
10
0
10
10
10
0
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
60
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _