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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC4
All Species:
21.52
Human Site:
S77
Identified Species:
52.59
UniProt:
Q5T4D3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T4D3
NP_001073137.1
741
82991
S77
F
W
G
S
R
L
S
S
N
T
S
H
K
S
Y
Chimpanzee
Pan troglodytes
XP_509717
790
88939
S126
F
W
G
S
R
L
S
S
N
T
S
H
K
S
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534177
1013
112724
S350
F
W
G
S
R
L
S
S
N
T
S
H
K
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG19
741
82944
N77
W
G
S
K
L
S
S
N
T
S
H
K
S
Y
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416968
790
89162
S77
F
W
G
S
K
L
S
S
N
T
S
H
K
S
Y
Frog
Xenopus laevis
Q6DCD5
836
94386
L82
L
N
Y
L
F
G
G
L
D
P
W
N
Y
H
L
Zebra Danio
Brachydanio rerio
NP_001166973
739
83162
S77
F
W
G
S
N
L
S
S
N
S
S
H
K
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VF81
705
80433
H77
S
L
L
S
S
D
S
H
K
S
F
R
P
L
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20144
690
77719
S86
F
W
G
R
S
I
S
S
S
N
S
H
K
S
Y
Sea Urchin
Strong. purpuratus
XP_787838
666
75633
R77
F
L
D
N
V
W
M
R
V
A
G
I
V
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
N.A.
68.3
N.A.
90.6
N.A.
N.A.
N.A.
79.7
33.7
68.2
N.A.
37.7
N.A.
36
39.4
Protein Similarity:
100
90.8
N.A.
70.7
N.A.
94.7
N.A.
N.A.
N.A.
87
51.6
81.1
N.A.
55.8
N.A.
53.7
57.3
P-Site Identity:
100
100
N.A.
100
N.A.
6.6
N.A.
N.A.
N.A.
93.3
0
86.6
N.A.
13.3
N.A.
66.6
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
26.6
N.A.
N.A.
N.A.
100
13.3
93.3
N.A.
20
N.A.
80
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
10
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
70
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
10
60
0
0
10
10
0
0
0
10
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
10
60
0
10
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
10
10
0
0
0
10
0
0
10
60
0
0
% K
% Leu:
10
20
10
10
10
50
0
10
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
10
0
0
10
50
10
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
30
0
0
10
0
0
0
10
0
0
20
% R
% Ser:
10
0
10
60
20
10
80
60
10
30
60
0
10
60
0
% S
% Thr:
0
0
0
0
0
0
0
0
10
40
0
0
0
0
10
% T
% Val:
0
0
0
0
10
0
0
0
10
0
0
0
10
0
0
% V
% Trp:
10
60
0
0
0
10
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
10
10
60
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _