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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC4
All Species:
23.64
Human Site:
T299
Identified Species:
57.78
UniProt:
Q5T4D3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T4D3
NP_001073137.1
741
82991
T299
G
T
G
P
P
A
F
T
E
V
D
N
P
A
S
Chimpanzee
Pan troglodytes
XP_509717
790
88939
T348
G
T
G
P
P
A
F
T
E
V
D
N
P
A
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534177
1013
112724
T571
G
T
G
P
P
A
F
T
E
V
D
N
P
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG19
741
82944
T299
G
T
G
P
P
A
F
T
E
V
D
N
P
A
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416968
790
89162
T297
G
T
G
P
P
A
F
T
E
V
D
N
P
A
S
Frog
Xenopus laevis
Q6DCD5
836
94386
T289
W
L
L
F
C
P
D
T
L
S
F
D
W
S
M
Zebra Danio
Brachydanio rerio
NP_001166973
739
83162
T296
G
T
G
P
P
S
F
T
E
V
D
N
P
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VF81
705
80433
H275
N
P
V
A
H
N
E
H
V
L
T
R
G
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20144
690
77719
Y283
N
Y
T
Y
I
W
L
Y
H
A
Y
L
L
V
I
Sea Urchin
Strong. purpuratus
XP_787838
666
75633
Q273
M
G
C
V
P
V
I
Q
T
P
L
D
P
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
N.A.
68.3
N.A.
90.6
N.A.
N.A.
N.A.
79.7
33.7
68.2
N.A.
37.7
N.A.
36
39.4
Protein Similarity:
100
90.8
N.A.
70.7
N.A.
94.7
N.A.
N.A.
N.A.
87
51.6
81.1
N.A.
55.8
N.A.
53.7
57.3
P-Site Identity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
100
6.6
93.3
N.A.
6.6
N.A.
0
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
100
20
100
N.A.
13.3
N.A.
0
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
50
0
0
0
10
0
0
0
60
0
% A
% Cys:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
60
20
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
60
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
60
0
0
0
10
0
0
0
0
% F
% Gly:
60
10
60
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
10
0
0
10
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
10
0
0
0
10
0
10
10
10
10
10
10
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
20
0
0
0
0
10
0
0
0
0
0
60
0
0
0
% N
% Pro:
0
10
0
60
70
10
0
0
0
10
0
0
70
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% R
% Ser:
0
0
0
0
0
10
0
0
0
10
0
0
0
10
70
% S
% Thr:
0
60
10
0
0
0
0
70
10
0
10
0
0
0
0
% T
% Val:
0
0
10
10
0
10
0
0
10
60
0
0
0
10
10
% V
% Trp:
10
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
10
0
10
0
0
0
10
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _