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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC4
All Species:
13.33
Human Site:
Y135
Identified Species:
32.59
UniProt:
Q5T4D3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T4D3
NP_001073137.1
741
82991
Y135
V
L
F
G
G
L
Q
Y
T
S
K
G
R
R
L
Chimpanzee
Pan troglodytes
XP_509717
790
88939
Y184
V
L
F
G
G
L
Q
Y
T
S
K
G
R
R
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534177
1013
112724
Y408
V
L
F
G
G
L
Q
Y
T
S
K
G
R
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG19
741
82944
Y134
V
L
F
G
G
L
Q
Y
T
G
K
G
Q
R
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416968
790
89162
F135
I
L
L
G
G
L
Q
F
T
N
K
G
R
R
L
Frog
Xenopus laevis
Q6DCD5
836
94386
G143
I
V
G
R
A
D
V
G
S
G
L
F
F
L
L
Zebra Danio
Brachydanio rerio
NP_001166973
739
83162
Q135
I
L
I
G
G
P
V
Q
D
G
K
G
A
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VF81
705
80433
R133
V
P
E
V
S
T
A
R
W
A
I
L
S
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20144
690
77719
F143
Q
L
E
H
I
F
D
F
F
N
I
A
F
S
A
Sea Urchin
Strong. purpuratus
XP_787838
666
75633
M133
M
V
L
C
A
V
A
M
L
C
K
E
Q
G
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
N.A.
68.3
N.A.
90.6
N.A.
N.A.
N.A.
79.7
33.7
68.2
N.A.
37.7
N.A.
36
39.4
Protein Similarity:
100
90.8
N.A.
70.7
N.A.
94.7
N.A.
N.A.
N.A.
87
51.6
81.1
N.A.
55.8
N.A.
53.7
57.3
P-Site Identity:
100
100
N.A.
100
N.A.
80
N.A.
N.A.
N.A.
73.3
6.6
40
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
N.A.
N.A.
N.A.
93.3
26.6
53.3
N.A.
13.3
N.A.
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
0
20
0
0
10
0
10
10
10
20
% A
% Cys:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
10
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
20
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
40
0
0
10
0
20
10
0
0
10
20
0
0
% F
% Gly:
0
0
10
60
60
0
0
10
0
30
0
60
0
10
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
30
0
10
0
10
0
0
0
0
0
20
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
70
0
0
10
0
% K
% Leu:
0
70
20
0
0
50
0
0
10
0
10
10
0
10
60
% L
% Met:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
50
10
0
0
0
0
20
0
0
% Q
% Arg:
0
0
0
10
0
0
0
10
0
0
0
0
40
50
0
% R
% Ser:
0
0
0
0
10
0
0
0
10
30
0
0
10
10
0
% S
% Thr:
0
0
0
0
0
10
0
0
50
0
0
0
0
0
0
% T
% Val:
50
20
0
10
0
10
20
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _