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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC4
All Species:
22.42
Human Site:
Y583
Identified Species:
54.81
UniProt:
Q5T4D3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T4D3
NP_001073137.1
741
82991
Y583
A
I
K
H
R
R
K
Y
P
D
C
Y
Y
N
L
Chimpanzee
Pan troglodytes
XP_509717
790
88939
Y632
A
I
K
H
R
R
K
Y
P
D
C
Y
Y
N
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534177
1013
112724
Y855
A
I
K
H
R
R
K
Y
P
D
C
Y
Y
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG19
741
82944
Y583
A
I
K
H
R
R
K
Y
P
D
C
Y
Y
N
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416968
790
89162
Y581
A
I
K
H
R
K
K
Y
P
D
C
Y
Y
N
L
Frog
Xenopus laevis
Q6DCD5
836
94386
V605
P
N
A
H
K
S
S
V
T
S
C
L
Y
N
L
Zebra Danio
Brachydanio rerio
NP_001166973
739
83162
Y581
A
I
R
F
R
K
K
Y
P
D
C
Y
Y
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VF81
705
80433
F545
A
L
K
Y
R
A
N
F
A
V
C
Y
Y
N
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20144
690
77719
H535
L
I
R
P
N
S
A
H
C
L
F
N
L
G
V
Sea Urchin
Strong. purpuratus
XP_787838
666
75633
G525
G
N
L
Y
L
V
L
G
N
T
D
Q
A
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
N.A.
68.3
N.A.
90.6
N.A.
N.A.
N.A.
79.7
33.7
68.2
N.A.
37.7
N.A.
36
39.4
Protein Similarity:
100
90.8
N.A.
70.7
N.A.
94.7
N.A.
N.A.
N.A.
87
51.6
81.1
N.A.
55.8
N.A.
53.7
57.3
P-Site Identity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
93.3
33.3
80
N.A.
46.6
N.A.
6.6
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
100
40
93.3
N.A.
73.3
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
0
10
0
0
10
10
0
10
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
80
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
60
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
10
0
0
10
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% G
% His:
0
0
0
60
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
60
0
10
20
60
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
10
0
10
0
10
0
0
10
0
10
10
10
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
20
0
0
10
0
10
0
10
0
0
10
0
80
0
% N
% Pro:
10
0
0
10
0
0
0
0
60
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
20
0
70
40
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
20
10
0
0
10
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
10
0
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
20
0
0
0
60
0
0
0
70
80
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _