KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC4
All Species:
9.09
Human Site:
Y97
Identified Species:
22.22
UniProt:
Q5T4D3
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T4D3
NP_001073137.1
741
82991
Y97
L
T
F
R
I
N
Y
Y
L
S
G
G
F
H
P
Chimpanzee
Pan troglodytes
XP_509717
790
88939
Y146
L
T
F
R
I
N
Y
Y
L
S
G
G
F
H
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534177
1013
112724
Y370
L
T
F
R
I
N
Y
Y
L
S
G
G
F
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG19
741
82944
L97
T
F
R
I
N
Y
Y
L
S
G
G
F
H
P
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416968
790
89162
L97
L
T
F
R
I
N
Y
L
F
A
G
G
F
Y
P
Frog
Xenopus laevis
Q6DCD5
836
94386
F102
H
S
A
V
T
G
L
F
T
N
L
C
K
A
L
Zebra Danio
Brachydanio rerio
NP_001166973
739
83162
L97
L
T
F
R
I
N
Y
L
L
A
G
G
L
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VF81
705
80433
L97
C
E
Y
A
L
L
G
L
S
A
A
H
M
K
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20144
690
77719
K106
F
T
F
W
L
N
Y
K
L
H
E
T
S
T
L
Sea Urchin
Strong. purpuratus
XP_787838
666
75633
F97
A
L
F
F
F
M
S
F
L
L
Y
T
T
V
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.9
N.A.
68.3
N.A.
90.6
N.A.
N.A.
N.A.
79.7
33.7
68.2
N.A.
37.7
N.A.
36
39.4
Protein Similarity:
100
90.8
N.A.
70.7
N.A.
94.7
N.A.
N.A.
N.A.
87
51.6
81.1
N.A.
55.8
N.A.
53.7
57.3
P-Site Identity:
100
100
N.A.
100
N.A.
13.3
N.A.
N.A.
N.A.
73.3
0
80
N.A.
0
N.A.
33.3
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
13.3
N.A.
N.A.
N.A.
86.6
20
86.6
N.A.
20
N.A.
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
0
0
0
0
30
10
0
0
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
10
10
70
10
10
0
0
20
10
0
0
10
40
0
10
% F
% Gly:
0
0
0
0
0
10
10
0
0
10
60
50
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
10
0
10
10
40
0
% H
% Ile:
0
0
0
10
50
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
10
10
0
% K
% Leu:
50
10
0
0
20
10
10
40
60
10
10
0
10
0
20
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
10
60
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
50
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
50
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
0
0
10
0
20
30
0
0
10
0
0
% S
% Thr:
10
60
0
0
10
0
0
0
10
0
0
20
10
10
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
10
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
70
30
0
0
10
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _