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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP5
All Species:
29.7
Human Site:
S418
Identified Species:
72.59
UniProt:
Q5T5C0
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T5C0
NP_001121187.1
1151
127573
S418
D
L
I
P
A
L
Y
S
V
G
A
R
Q
K
R
Chimpanzee
Pan troglodytes
XP_516678
1303
144261
S548
D
L
I
L
V
L
Y
S
I
G
V
K
H
K
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533442
1260
139162
S527
D
L
I
P
A
L
Y
S
V
G
A
R
Q
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K400
1152
127638
S419
D
L
I
P
A
L
Y
S
V
G
A
R
Q
K
R
Rat
Rattus norvegicus
Q9WU70
1152
127641
S419
D
L
I
P
A
L
Y
S
V
G
A
R
Q
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507080
1121
123964
S424
E
L
I
P
A
L
Y
S
V
G
V
R
Q
K
R
Chicken
Gallus gallus
XP_419658
1115
123181
S419
D
L
I
P
A
L
Y
S
V
G
A
R
Q
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5SQE2
1159
128185
S432
D
I
I
P
V
L
Y
S
I
G
A
K
H
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08111
1161
126874
R398
S
V
Y
E
S
I
L
R
A
G
D
E
Q
D
I
Honey Bee
Apis mellifera
XP_391820
1090
120734
V401
A
D
C
P
S
D
L
V
P
A
F
Y
S
V
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.2
N.A.
89.9
N.A.
96.8
96.8
N.A.
92
90.3
N.A.
63.8
N.A.
22.1
50.5
N.A.
N.A.
Protein Similarity:
100
72.8
N.A.
90.5
N.A.
98.3
98.2
N.A.
94.8
93.3
N.A.
79.2
N.A.
40.7
68.4
N.A.
N.A.
P-Site Identity:
100
53.3
N.A.
100
N.A.
100
100
N.A.
86.6
100
N.A.
60
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
73.3
N.A.
100
N.A.
100
100
N.A.
93.3
100
N.A.
86.6
N.A.
33.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
60
0
0
0
10
10
60
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
70
10
0
0
0
10
0
0
0
0
10
0
0
10
0
% D
% Glu:
10
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
90
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% H
% Ile:
0
10
80
0
0
10
0
0
20
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
20
0
80
20
% K
% Leu:
0
70
0
10
0
80
20
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
80
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
70
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
60
0
0
60
% R
% Ser:
10
0
0
0
20
0
0
80
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
20
0
0
10
60
0
20
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
80
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _