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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STXBP5 All Species: 20.61
Human Site: S904 Identified Species: 50.37
UniProt: Q5T5C0 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T5C0 NP_001121187.1 1151 127573 S904 R P V S V S P S S S Q E I S E
Chimpanzee Pan troglodytes XP_516678 1303 144261 S1056 K V V M N S S S A S Q E I G D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533442 1260 139162 S1013 R P V S V S P S S S Q E I S E
Cat Felis silvestris
Mouse Mus musculus Q8K400 1152 127638 S905 R P V S V S P S S S Q E I S E
Rat Rattus norvegicus Q9WU70 1152 127641 S905 R P V S V S P S S S Q E I S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507080 1121 123964 K891 Y A V I C S E K Q A K V I S L
Chicken Gallus gallus XP_419658 1115 123181 Q887 A V I C S E K Q A K V I S L P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5SQE2 1159 128185 S916 L V N F S P S S S Q E A C G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08111 1161 126874 S893 I S G S L A V S R G D V Y N E
Honey Bee Apis mellifera XP_391820 1090 120734 T863 V I K A E I T T L K D N V C L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.2 N.A. 89.9 N.A. 96.8 96.8 N.A. 92 90.3 N.A. 63.8 N.A. 22.1 50.5 N.A. N.A.
Protein Similarity: 100 72.8 N.A. 90.5 N.A. 98.3 98.2 N.A. 94.8 93.3 N.A. 79.2 N.A. 40.7 68.4 N.A. N.A.
P-Site Identity: 100 46.6 N.A. 100 N.A. 100 100 N.A. 26.6 0 N.A. 13.3 N.A. 20 0 N.A. N.A.
P-Site Similarity: 100 66.6 N.A. 100 N.A. 100 100 N.A. 40 13.3 N.A. 26.6 N.A. 40 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 10 0 10 0 0 20 10 0 10 0 0 0 % A
% Cys: 0 0 0 10 10 0 0 0 0 0 0 0 10 10 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 20 % D
% Glu: 0 0 0 0 10 10 10 0 0 0 10 50 0 0 50 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 10 0 0 0 20 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 10 10 0 10 0 0 0 0 0 10 60 0 0 % I
% Lys: 10 0 10 0 0 0 10 10 0 20 10 0 0 0 0 % K
% Leu: 10 0 0 0 10 0 0 0 10 0 0 0 0 10 20 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 10 0 0 0 0 0 0 10 0 10 0 % N
% Pro: 0 40 0 0 0 10 40 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 10 10 10 50 0 0 0 0 % Q
% Arg: 40 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 10 0 50 20 60 20 70 50 50 0 0 10 50 0 % S
% Thr: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % T
% Val: 10 30 60 0 40 0 10 0 0 0 10 20 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _