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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCAF12 All Species: 23.33
Human Site: S45 Identified Species: 51.33
UniProt: Q5T6F0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T6F0 NP_056212.1 453 50517 S45 R L P P V K R S L V Y Y L K N
Chimpanzee Pan troglodytes XP_001160240 453 50267 S45 R L P P V K R S L V Y Y L K N
Rhesus Macaque Macaca mulatta XP_001098592 453 50462 S45 R L P P V K R S L V Y Y L K N
Dog Lupus familis XP_538706 453 50544 S45 R L P P V K R S L V Y Y L K N
Cat Felis silvestris
Mouse Mus musculus Q8BGZ3 453 50441 S45 R L P P V K R S L V Y Y L K N
Rat Rattus norvegicus XP_001059949 453 50440 S45 R L P P V K R S L V Y Y L K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F3R7 427 47600 W30 L Y G E Q Y G W D H S V H K R
Frog Xenopus laevis Q63ZP7 446 49593 L45 K K S L V F Y L K S R E L K P
Zebra Danio Brachydanio rerio Q08BB3 482 53852 V50 W Q S R R S V V C S V R G R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396383 459 52162 S52 D F I C Y E S S D D E A E T V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791553 435 48529 V38 G D P E S A S V F H H I R S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96 98.9 99.3 N.A. 98.4 98.4 N.A. N.A. 85.4 77.9 70.5 N.A. N.A. 42.4 N.A. 42.3
Protein Similarity: 100 96.9 99.5 99.5 N.A. 99.1 98.9 N.A. N.A. 89.1 87.1 78.6 N.A. N.A. 59.9 N.A. 60.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 6.6 20 0 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 6.6 26.6 6.6 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 10 10 0 0 0 0 0 0 19 10 0 0 0 0 0 % D
% Glu: 0 0 0 19 0 10 0 0 0 0 10 10 10 0 10 % E
% Phe: 0 10 0 0 0 10 0 0 10 0 0 0 0 0 0 % F
% Gly: 10 0 10 0 0 0 10 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 19 10 0 10 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 10 10 0 0 0 55 0 0 10 0 0 0 0 73 0 % K
% Leu: 10 55 0 10 0 0 0 10 55 0 0 0 64 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 55 % N
% Pro: 0 0 64 55 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 55 0 0 10 10 0 55 0 0 0 10 10 10 10 19 % R
% Ser: 0 0 19 0 10 10 19 64 0 19 10 0 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % T
% Val: 0 0 0 0 64 0 10 19 0 55 10 10 0 0 10 % V
% Trp: 10 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 10 10 10 0 0 0 55 55 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _