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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF12
All Species:
27.88
Human Site:
T354
Identified Species:
61.33
UniProt:
Q5T6F0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T6F0
NP_056212.1
453
50517
T354
S
F
Y
E
H
I
I
T
V
G
T
G
Q
G
S
Chimpanzee
Pan troglodytes
XP_001160240
453
50267
T354
S
F
Y
E
H
I
I
T
V
G
T
G
Q
G
S
Rhesus Macaque
Macaca mulatta
XP_001098592
453
50462
T354
S
F
Y
E
H
I
I
T
V
G
T
G
Q
G
S
Dog
Lupus familis
XP_538706
453
50544
T354
S
F
Y
E
H
I
I
T
V
G
T
G
Q
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGZ3
453
50441
T354
S
F
Y
E
H
I
I
T
V
G
T
G
Q
G
S
Rat
Rattus norvegicus
XP_001059949
453
50440
T354
S
F
Y
E
H
I
I
T
V
G
T
G
Q
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3R7
427
47600
T329
E
H
I
I
T
V
G
T
G
H
G
S
L
L
F
Frog
Xenopus laevis
Q63ZP7
446
49593
I347
S
V
S
F
Y
E
H
I
V
T
V
G
T
G
Q
Zebra Danio
Brachydanio rerio
Q08BB3
482
53852
T383
S
F
Y
E
H
I
V
T
V
G
T
G
Q
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396383
459
52162
R360
R
Y
S
G
C
G
I
R
S
V
S
F
Q
G
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791553
435
48529
V337
R
G
S
G
V
R
S
V
S
F
M
D
G
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
98.9
99.3
N.A.
98.4
98.4
N.A.
N.A.
85.4
77.9
70.5
N.A.
N.A.
42.4
N.A.
42.3
Protein Similarity:
100
96.9
99.5
99.5
N.A.
99.1
98.9
N.A.
N.A.
89.1
87.1
78.6
N.A.
N.A.
59.9
N.A.
60.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
26.6
93.3
N.A.
N.A.
26.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
33.3
100
N.A.
N.A.
40
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
10
0
0
64
0
10
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
64
0
10
0
0
0
0
0
10
0
10
0
0
10
% F
% Gly:
0
10
0
19
0
10
10
0
10
64
10
73
10
82
0
% G
% His:
0
10
0
0
64
0
10
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
10
0
64
64
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
73
0
10
% Q
% Arg:
19
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% R
% Ser:
73
0
28
0
0
0
10
0
19
0
10
10
0
0
73
% S
% Thr:
0
0
0
0
10
0
0
73
0
10
64
0
10
0
0
% T
% Val:
0
10
0
0
10
10
10
10
73
10
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
64
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _