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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF12
All Species:
22.73
Human Site:
Y275
Identified Species:
50
UniProt:
Q5T6F0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T6F0
NP_056212.1
453
50517
Y275
G
A
V
S
L
D
G
Y
F
H
L
W
K
A
E
Chimpanzee
Pan troglodytes
XP_001160240
453
50267
Q275
C
N
G
T
I
S
A
Q
S
N
L
H
L
P
G
Rhesus Macaque
Macaca mulatta
XP_001098592
453
50462
Y275
G
A
V
S
L
D
G
Y
F
H
L
W
K
A
E
Dog
Lupus familis
XP_538706
453
50544
Y275
G
A
V
S
L
D
G
Y
F
H
L
W
K
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGZ3
453
50441
Y275
G
A
V
S
L
D
G
Y
F
H
L
W
K
A
E
Rat
Rattus norvegicus
XP_001059949
453
50440
Y275
G
A
V
S
L
D
G
Y
F
H
L
W
K
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F3R7
427
47600
L250
S
L
D
G
Y
F
H
L
W
K
A
E
H
T
L
Frog
Xenopus laevis
Q63ZP7
446
49593
D268
E
L
G
A
V
S
L
D
G
F
F
H
L
W
K
Zebra Danio
Brachydanio rerio
Q08BB3
482
53852
Y304
G
A
V
S
L
D
G
Y
F
H
L
W
K
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396383
459
52162
R281
V
R
A
L
V
F
N
R
T
Y
K
E
I
A
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791553
435
48529
K258
L
E
Y
S
Q
H
T
K
E
L
A
S
L
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
98.9
99.3
N.A.
98.4
98.4
N.A.
N.A.
85.4
77.9
70.5
N.A.
N.A.
42.4
N.A.
42.3
Protein Similarity:
100
96.9
99.5
99.5
N.A.
99.1
98.9
N.A.
N.A.
89.1
87.1
78.6
N.A.
N.A.
59.9
N.A.
60.2
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
N.A.
0
0
100
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
N.A.
6.6
20
100
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
55
10
10
0
0
10
0
0
0
19
0
0
64
19
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
55
0
10
0
0
0
0
0
0
0
% D
% Glu:
10
10
0
0
0
0
0
0
10
0
0
19
0
0
55
% E
% Phe:
0
0
0
0
0
19
0
0
55
10
10
0
0
0
0
% F
% Gly:
55
0
19
10
0
0
55
0
10
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
10
10
0
0
55
0
19
10
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
10
10
0
55
0
10
% K
% Leu:
10
19
0
10
55
0
10
10
0
10
64
0
28
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
10
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
64
0
19
0
0
10
0
0
10
0
10
0
% S
% Thr:
0
0
0
10
0
0
10
0
10
0
0
0
0
10
0
% T
% Val:
10
0
55
0
19
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
55
0
10
0
% W
% Tyr:
0
0
10
0
10
0
0
55
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _