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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPRC6A
All Species:
17.88
Human Site:
Y474
Identified Species:
43.7
UniProt:
Q5T6X5
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T6X5
NP_683766.2
926
104753
Y474
H
G
D
L
N
T
G
Y
D
V
V
L
W
K
E
Chimpanzee
Pan troglodytes
Q717C2
852
93438
H405
Y
S
V
A
Q
A
L
H
N
T
L
Q
C
N
A
Rhesus Macaque
Macaca mulatta
A3QP01
839
95041
V392
V
Y
S
V
Y
S
A
V
Y
A
V
A
H
A
L
Dog
Lupus familis
XP_541212
928
104506
Y474
H
G
D
M
N
T
G
Y
D
V
V
L
W
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4Z6
928
104195
Y474
H
G
D
L
N
T
G
Y
D
V
V
L
W
K
E
Rat
Rattus norvegicus
Q70VB1
928
104335
Y474
H
G
D
L
N
T
G
Y
E
V
V
L
W
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515899
1088
120096
W494
G
N
Y
S
I
I
N
W
H
L
S
P
L
D
G
Chicken
Gallus gallus
XP_426177
996
111550
Y471
K
G
D
L
S
S
G
Y
D
V
L
L
W
K
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
W419
D
S
T
A
L
Q
P
W
E
L
L
R
Q
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
Q507
S
E
V
K
F
D
R
Q
G
D
G
L
A
R
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.2
24.6
86.9
N.A.
80
80
N.A.
30.5
58.2
N.A.
41.7
N.A.
24.8
N.A.
N.A.
N.A.
Protein Similarity:
100
47
43.8
92.3
N.A.
87.2
87.5
N.A.
48.3
71.4
N.A.
60.2
N.A.
44.9
N.A.
N.A.
N.A.
P-Site Identity:
100
0
6.6
93.3
N.A.
100
93.3
N.A.
0
73.3
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
20
100
N.A.
100
100
N.A.
13.3
93.3
N.A.
26.6
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
10
10
0
0
10
0
10
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
10
0
50
0
0
10
0
0
40
10
0
0
0
10
0
% D
% Glu:
0
10
0
0
0
0
0
0
20
0
0
0
0
0
50
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
50
0
0
0
0
50
0
10
0
10
0
0
0
10
% G
% His:
40
0
0
0
0
0
0
10
10
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
10
0
0
0
0
0
0
0
0
0
50
0
% K
% Leu:
0
0
0
40
10
0
10
0
0
20
30
60
10
10
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
40
0
10
0
10
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
10
10
0
10
0
0
0
10
10
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
10
0
10
10
% R
% Ser:
10
20
10
10
10
20
0
0
0
0
10
0
0
0
0
% S
% Thr:
0
0
10
0
0
40
0
0
0
10
0
0
0
0
0
% T
% Val:
10
0
20
10
0
0
0
10
0
50
50
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
20
0
0
0
0
50
0
0
% W
% Tyr:
10
10
10
0
10
0
0
50
10
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _