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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSTD2
All Species:
13.03
Human Site:
Y275
Identified Species:
31.85
UniProt:
Q5T7W7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T7W7
NP_640339.4
516
58263
Y275
I
S
P
K
K
I
S
Y
K
K
P
G
I
H
L
Chimpanzee
Pan troglodytes
XP_520137
516
58228
Y275
I
S
P
K
K
I
S
Y
K
K
P
G
I
H
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538744
526
59728
Y274
I
S
P
N
K
I
S
Y
K
K
P
G
I
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3U269
495
55368
Y274
I
S
P
S
Q
V
S
Y
K
K
P
G
I
H
L
Rat
Rattus norvegicus
NP_001102133
493
55455
M265
V
F
E
E
I
V
P
M
G
I
S
P
S
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516562
177
19920
Chicken
Gallus gallus
XP_424952
466
51604
L245
Y
K
E
T
G
I
H
L
T
P
Q
E
F
H
R
Frog
Xenopus laevis
NP_001108262
482
54555
E261
P
M
G
I
E
P
H
E
V
S
Y
K
V
T
A
Zebra Danio
Brachydanio rerio
XP_001920522
324
36398
L103
H
S
A
E
I
H
Q
L
T
S
D
S
L
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793430
519
58876
F268
M
D
P
M
L
V
S
F
K
D
A
G
C
H
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
N.A.
84.4
N.A.
77.5
76.9
N.A.
23.6
56.7
56.2
29.2
N.A.
N.A.
N.A.
N.A.
39.6
Protein Similarity:
100
99.6
N.A.
89.3
N.A.
86.4
85.8
N.A.
29.8
70.7
70.3
41.6
N.A.
N.A.
N.A.
N.A.
58
P-Site Identity:
100
100
N.A.
93.3
N.A.
80
0
N.A.
0
13.3
0
13.3
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
26.6
N.A.
0
13.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
10
10
0
0
0
0
% D
% Glu:
0
0
20
20
10
0
0
10
0
0
0
10
0
10
0
% E
% Phe:
0
10
0
0
0
0
0
10
0
0
0
0
10
0
0
% F
% Gly:
0
0
10
0
10
0
0
0
10
0
0
50
0
0
0
% G
% His:
10
0
0
0
0
10
20
0
0
0
0
0
0
60
0
% H
% Ile:
40
0
0
10
20
40
0
0
0
10
0
0
40
0
0
% I
% Lys:
0
10
0
20
30
0
0
0
50
40
0
10
0
10
0
% K
% Leu:
0
0
0
0
10
0
0
20
0
0
0
0
10
0
60
% L
% Met:
10
10
0
10
0
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
50
0
0
10
10
0
0
10
40
10
0
0
0
% P
% Gln:
0
0
0
0
10
0
10
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
0
50
0
10
0
0
50
0
0
20
10
10
10
0
0
% S
% Thr:
0
0
0
10
0
0
0
0
20
0
0
0
0
10
0
% T
% Val:
10
0
0
0
0
30
0
0
10
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
40
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _