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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C1orf59 All Species: 18.79
Human Site: S242 Identified Species: 45.93
UniProt: Q5T8I9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T8I9 NP_001096062.1 393 44525 S242 K A T E S C L S E Q H D Q H V
Chimpanzee Pan troglodytes XP_524784 401 45254 S250 K A T E S C L S E Q H D Q H V
Rhesus Macaque Macaca mulatta XP_001087383 563 62721 S412 R A T E A C V S E Q H D Q H V
Dog Lupus familis XP_537046 411 46700 S265 K A T E S C I S T P E E H V Y
Cat Felis silvestris
Mouse Mus musculus Q8CAE2 395 44902 S243 K L S K P S V S Q Q C D Q H V
Rat Rattus norvegicus Q32PY6 394 45068 S242 K L S E P S A S Q Q R D Q H V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514139 180 20668 L41 K P K K V A D L G C A D C S L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q568P9 402 46106 S222 D G V N R S M S N A E H L E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610732 391 45551 L240 I F V R K D M L E M Q L V N P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794037 618 69298 E236 P S K D C L A E S T D E D L Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97 67.5 54.2 N.A. 68.6 70.3 N.A. 29 N.A. N.A. 36.5 N.A. 29.2 N.A. N.A. 27
Protein Similarity: 100 97 68.9 72.7 N.A. 83.2 82.7 N.A. 36.6 N.A. N.A. 53.4 N.A. 46.3 N.A. N.A. 40.1
P-Site Identity: 100 100 80 46.6 N.A. 46.6 53.3 N.A. 13.3 N.A. N.A. 6.6 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 100 100 60 N.A. 73.3 66.6 N.A. 26.6 N.A. N.A. 13.3 N.A. 20 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 40 0 0 10 10 20 0 0 10 10 0 0 0 0 % A
% Cys: 0 0 0 0 10 40 0 0 0 10 10 0 10 0 0 % C
% Asp: 10 0 0 10 0 10 10 0 0 0 10 60 10 0 0 % D
% Glu: 0 0 0 50 0 0 0 10 40 0 20 20 0 10 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 30 10 10 50 0 % H
% Ile: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 60 0 20 20 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 20 0 0 0 10 20 20 0 0 0 10 10 10 10 % L
% Met: 0 0 0 0 0 0 20 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 10 0 0 0 0 10 0 % N
% Pro: 10 10 0 0 20 0 0 0 0 10 0 0 0 0 20 % P
% Gln: 0 0 0 0 0 0 0 0 20 50 10 0 50 0 10 % Q
% Arg: 10 0 0 10 10 0 0 0 0 0 10 0 0 0 0 % R
% Ser: 0 10 20 0 30 30 0 70 10 0 0 0 0 10 0 % S
% Thr: 0 0 40 0 0 0 0 0 10 10 0 0 0 0 0 % T
% Val: 0 0 20 0 10 0 20 0 0 0 0 0 10 10 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _