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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C1orf59
All Species:
14.85
Human Site:
S281
Identified Species:
36.3
UniProt:
Q5T8I9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T8I9
NP_001096062.1
393
44525
S281
E
V
S
Q
Q
V
E
S
L
R
V
S
H
L
P
Chimpanzee
Pan troglodytes
XP_524784
401
45254
S289
E
V
S
Q
Q
V
E
S
L
R
V
S
H
L
P
Rhesus Macaque
Macaca mulatta
XP_001087383
563
62721
S451
E
V
S
Q
Q
V
E
S
L
R
V
S
H
L
P
Dog
Lupus familis
XP_537046
411
46700
S303
E
V
L
R
A
S
N
S
M
R
L
R
F
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CAE2
395
44902
R282
E
L
L
I
Q
V
D
R
L
R
L
R
Y
Q
R
Rat
Rattus norvegicus
Q32PY6
394
45068
R281
E
L
L
I
Q
V
D
R
L
R
L
R
H
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514139
180
20668
T79
K
E
K
M
H
R
L
T
P
L
P
G
D
Y
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q568P9
402
46106
H263
E
V
L
Y
E
A
Q
H
L
R
Q
Q
W
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610732
391
45551
L282
T
R
T
E
K
E
K
L
W
T
E
V
Q
I
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794037
618
69298
S405
Q
K
S
Q
E
A
C
S
K
D
V
S
D
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
67.5
54.2
N.A.
68.6
70.3
N.A.
29
N.A.
N.A.
36.5
N.A.
29.2
N.A.
N.A.
27
Protein Similarity:
100
97
68.9
72.7
N.A.
83.2
82.7
N.A.
36.6
N.A.
N.A.
53.4
N.A.
46.3
N.A.
N.A.
40.1
P-Site Identity:
100
100
100
26.6
N.A.
33.3
40
N.A.
0
N.A.
N.A.
33.3
N.A.
0
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
53.3
N.A.
60
60
N.A.
13.3
N.A.
N.A.
46.6
N.A.
33.3
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
20
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
20
0
0
10
0
0
20
0
0
% D
% Glu:
70
10
0
10
20
10
30
0
0
0
10
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
10
0
0
10
0
0
0
0
40
0
0
% H
% Ile:
0
0
0
20
0
0
0
0
0
0
0
0
0
20
10
% I
% Lys:
10
10
10
0
10
0
10
0
10
0
0
0
0
0
0
% K
% Leu:
0
20
40
0
0
0
10
10
60
10
30
0
0
50
10
% L
% Met:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
40
% P
% Gln:
10
0
0
40
50
0
10
0
0
0
10
10
10
20
0
% Q
% Arg:
0
10
0
10
0
10
0
20
0
70
0
30
0
0
20
% R
% Ser:
0
0
40
0
0
10
0
50
0
0
0
40
0
0
0
% S
% Thr:
10
0
10
0
0
0
0
10
0
10
0
0
0
0
0
% T
% Val:
0
50
0
0
0
50
0
0
0
0
40
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _